Biomedical metal–organic framework materials: perspectives and challenges

A Wang, M Walden, R Ettlinger… - Advanced Functional …, 2023 - Wiley Online Library
Metal–organic framework (MOF) materials are gaining significant interest in biomedical
research, owing to their high porosity, crystallinity, and structural and compositional diversity …

Oxygen releasing patches based on carbohydrate polymer and protein hydrogels for diabetic wound healing: A review

A Al Mamun, A Ullah, MEH Chowdhury… - International journal of …, 2023 - Elsevier
Diabetic wounds are among the major healthcare challenges, consuming billions of dollars
of resources and resulting in high numbers of morbidity and mortality every year. Lack of …

An orally-administered nanotherapeutics with carbon monoxide supplying for inflammatory bowel disease therapy by scavenging oxidative stress and restoring gut …

X Zhang, Z Yuan, J Wu, Y He, G Lu, D Zhang, Y Zhao… - ACS …, 2023 - ACS Publications
Traditional drug-based treatments for inflammatory bowel disease (IBD) have significant
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …

Development of Spleen Targeting H2S Donor Loaded Liposome for the Effective Systemic Immunomodulation and Treatment of Inflammatory Bowel Disease

C Oh, W Lee, J Park, J Choi, S Lee, S Li, HN Jung… - ACS …, 2023 - ACS Publications
Nanoparticles are primarily taken up by immune cells after systemic administration. Thus,
they are considered an ideal drug delivery vehicle for immunomodulation. Because the …

Regulation Strategy of Nanostructured Engineering on IndiumBased Materials for Electrocatalytic Conversion of CO2

W Wu, Y Tong, P Chen - Small, 2024 - Wiley Online Library
Electrochemical carbon dioxide reduction (CO2RR), as an emerging technology, can
combine with sustainable energies to convert CO2 into high valueadded products …

[HTML][HTML] An ischemic area-targeting, peroxynitrite-responsive, biomimetic carbon monoxide nanogenerator for preventing myocardial ischemia-reperfusion injury

J Zhang, L Liu, Z Dong, X Lu, W Hong, J Liu, X Zou… - Bioactive Materials, 2023 - Elsevier
Myocardial ischemia-reperfusion (MI/R) injury is common in patients who undergo
revascularization therapy for myocardial infarction, often leading to cardiac dysfunction …

LowCost, HighPressureSynthesized OxygenEntrapping Materials to Improve Treatment of Solid Tumors

J Bi, E Witt, VA Voltarelli, VR Feig… - Advanced …, 2023 - Wiley Online Library
Tumor hypoxia drives resistance to many cancer therapies, including radiotherapy and
chemotherapy. Methods that increase tumor oxygen pressures, such as hyperbaric oxygen …

Structural insights into microbial one-carbon metabolic enzymes Ni–Fe–S-dependent carbon monoxide dehydrogenases and acetyl-CoA synthases

A Biester, AN Marcano-Delgado, CL Drennan - Biochemistry, 2022 - ACS Publications
Ni–Fe–S-dependent carbon monoxide dehydrogenases (CODHs) are enzymes that
interconvert CO and CO2 by using their catalytic Ni–Fe–S C-cluster and their Fe–S B-and D …

Single-Cell Analysis Reveals Cxcl14+ Fibroblast Accumulation in Regenerating Diabetic Wounds Treated by Hydrogel-Delivering Carbon Monoxide

Y Li, L Sun, R Chen, W Ni, Y Liang, H Zhang… - ACS Central …, 2024 - ACS Publications
Nonhealing skin wounds are a problematic complication associated with diabetes.
Therapeutic gases delivered by biomaterials have demonstrated powerful wound healing …

Transdermal carbon monoxide delivery

M Ruopp, S Reiländer, D Haas, I Caruana… - Journal of Controlled …, 2023 - Elsevier
Overuse injuries or acute trauma in joints often lead to painful tendinopathy, and
pharmacological treatment effects are limited. The site of the disease is hard to reach with …