Immune checkpoint therapies (ICT) can reinvigorate the effector functions of anti-tumour T
cells, improving cancer patient outcomes. Anti-tumour T cells are initially formed during their …

Uveal melanoma (UM) is an aggressive and deadly neoplasm. In recent decades, great
efforts have been made to obtain a more comprehensive understanding of genetics …

Choroidal melanoma is a devastating disease that causes visual loss and a high mortality
rate due to metastasis. Luteolin, a potential anticancer compound, is widely found in natural …

Uveal melanoma (UM), a distinct subtype of melanoma, presents unique challenges in its
clinical management due to its complex molecular landscape and tendency for liver …

Uveal melanoma (UM) is a highly aggressive and fatal tumor in the eye, and due the special
biology of UM, immunotherapy showed little effect in UM patients. To improve the efficacy of …

Introduction: Epidemiological studies of ocular melanomas have largely focused on
Caucasian populations. This study reviewed the course and outcomes of uveal melanoma …

Uveal cancer (UM) offers a complex molecular landscape characterized by substantial
heterogeneity, both on the genetic and epigenetic levels. This heterogeneity plays a critical …

Uveal melanoma (UM) is a rare cancer of the eye with 50% metastasis rate. In contrast to
cutaneous melanoma, immune checkpoint inhibitors are largely ineffective. Previous studies …

Ocular neoplasms, despite their rarity, pose a significant problem in contemporary
ophthalmic oncology. The diagnosis of a tumor in the organ of vision often causes the need …