[HTML][HTML] Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic …
Immune checkpoint therapies (ICT) can reinvigorate the effector functions of anti-tumour T
cells, improving cancer patient outcomes. Anti-tumour T cells are initially formed during their …
cells, improving cancer patient outcomes. Anti-tumour T cells are initially formed during their …
Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology
T Strub, A Martel, S Nahon-Esteve, S Baillif… - Progress in Retinal and …, 2021 - Elsevier
Uveal melanoma (UM) is an aggressive and deadly neoplasm. In recent decades, great
efforts have been made to obtain a more comprehensive understanding of genetics …
efforts have been made to obtain a more comprehensive understanding of genetics …
Luteolin inhibits the proliferation, adhesion, migration and invasion of choroidal melanoma cells in vitro
ML Shi, YF Chen, WQ Wu, Y Lai, Q Jin, WL Qiu… - Experimental Eye …, 2021 - Elsevier
Choroidal melanoma is a devastating disease that causes visual loss and a high mortality
rate due to metastasis. Luteolin, a potential anticancer compound, is widely found in natural …
rate due to metastasis. Luteolin, a potential anticancer compound, is widely found in natural …
[HTML][HTML] Recent Advances in Molecular and Genetic Research on Uveal Melanoma
A Fuentes-Rodriguez, A Mitchell, SL Guérin… - Cells, 2024 - mdpi.com
Uveal melanoma (UM), a distinct subtype of melanoma, presents unique challenges in its
clinical management due to its complex molecular landscape and tendency for liver …
clinical management due to its complex molecular landscape and tendency for liver …
Single cell RNA-sequencing in uveal melanoma: advances in heterogeneity, tumor microenvironment and immunotherapy
S Tang, Y Zhang, S Huang, T Zhu, X Huang - Frontiers in Immunology, 2024 - frontiersin.org
Uveal melanoma (UM) is a highly aggressive and fatal tumor in the eye, and due the special
biology of UM, immunotherapy showed little effect in UM patients. To improve the efficacy of …
biology of UM, immunotherapy showed little effect in UM patients. To improve the efficacy of …
[PDF][PDF] Uveal and conjunctival melanomas: disease course and outcomes in Chinese patients
JYY Chan, SC Lam, HKL Yuen - Hong Kong Med J, 2023 - researchgate.net
Introduction: Epidemiological studies of ocular melanomas have largely focused on
Caucasian populations. This study reviewed the course and outcomes of uveal melanoma …
Caucasian populations. This study reviewed the course and outcomes of uveal melanoma …
[HTML][HTML] Heterogeneity and molecular landscape of melanoma: implications for targeted therapy
Uveal cancer (UM) offers a complex molecular landscape characterized by substantial
heterogeneity, both on the genetic and epigenetic levels. This heterogeneity plays a critical …
heterogeneity, both on the genetic and epigenetic levels. This heterogeneity plays a critical …
Human Endogenous Retroviruses Profiling in Metastatic Uveal Melanoma
T Fei - 2023 - search.proquest.com
Uveal melanoma (UM) is a rare cancer of the eye with 50% metastasis rate. In contrast to
cutaneous melanoma, immune checkpoint inhibitors are largely ineffective. Previous studies …
cutaneous melanoma, immune checkpoint inhibitors are largely ineffective. Previous studies …
[PDF][PDF] Modern therapy of eye neoplasms
M Witek, A Toboła, K Ciepiaszuk… - Advances in Biomedical … - researchgate.net
Ocular neoplasms, despite their rarity, pose a significant problem in contemporary
ophthalmic oncology. The diagnosis of a tumor in the organ of vision often causes the need …
ophthalmic oncology. The diagnosis of a tumor in the organ of vision often causes the need …