Objective Intra-operative blood loss is a significant complication of major lower limb
amputation (MLLA). This systematic review and meta-analysis assessed the effect of …

Background Patients with diabetes and peripheral arterial disease are at increased risk of
minor amputation. The aim of study was to assess the rate of re-amputations and death after …

Amputation is a clinical intervention which can have substantial impacts on the patient's
quality of life and wellbeing, and the existing literature demonstrates how adjustment to …

Background Decision-making when considering major lower limb amputation is complex
and requires individualized outcome estimation. It is unknown how accurate healthcare …

Background Lower limb amputation (LLA) is typically described as 'clean surgery', but
surgical-site infection (SSI) rates are high and there is significant variation in antibiotic …

Objectives Randomised controlled trial of the effect of a perineural infusion of
levobupivacaine on moderate/severe phantom limb pain 6 months after major lower limb …

Background The accuracy with which healthcare professionals (HCPs) and risk prediction
tools predict outcomes after major lower limb amputation (MLLA) is uncertain. The aim of this …

Background To investigate the effect of tourniquet use on outcomes after major lower limb
amputation (MLLA) due to peripheral arterial disease or complications from diabetes …

Background Through-knee amputation (TKA) carries potential biomechanical advantages
over above knee amputation (AKA) in patients unsuitable for a below-knee amputation …

Purpose Rehabilitation experiences of lower limb amputees with poorer physical health
have not been fully explored. This study aimed to qualitatively explore experiences of …