[HTML][HTML] Role of T Lymphocytes in Glioma Immune Microenvironment: Two Sides of a Coin
Simple Summary Gliomas are diverse types of tumors originating from glial cells. Among
these tumors, glioblastoma multiforme (GBM) is the most aggressive form and has a poor …
these tumors, glioblastoma multiforme (GBM) is the most aggressive form and has a poor …
Immunoediting Dynamics in Glioblastoma: Implications for Immunotherapy Approaches
Glioblastoma is an aggressive primary brain tumor that poses many therapeutic difficulties
because of the high rate of proliferation, genetic variability, and its immunosuppressive …
because of the high rate of proliferation, genetic variability, and its immunosuppressive …
CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy
SP Wolf, M Leisegang, M Steiner, V Wallace… - Science …, 2024 - science.org
Cancers eventually kill hosts even when infiltrated by cancer-specific T cells. We examined
whether cancer-specific T cell receptors of CD4+ T cells (CD4TCRs) from tumor-bearing …
whether cancer-specific T cell receptors of CD4+ T cells (CD4TCRs) from tumor-bearing …
Anti-Cancer Effect of Neural Stem Cells Transfected with Carboxylesterase and sTRAIL Genes in Animals with Brain Lesions of Lung Cancer
JH Kim, JS Ahn, DS Lee, SH Hong, HJ Lee - Pharmaceuticals, 2023 - mdpi.com
A metastatic brain tumor is the most common type of malignancy in the central nervous
system, which is one of the leading causes of death in patients with lung cancer. The …
system, which is one of the leading causes of death in patients with lung cancer. The …
One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication
SP Wolf, V Anastasopoulou, K Drousch, MI Diehl… - Clinical Cancer …, 2024 - AACR
Purpose: To achieve eradication of solid tumors, we examined how many neoantigens need
to be targeted with how many T-cell receptors (TCR) by which type of T cells. Experimental …
to be targeted with how many T-cell receptors (TCR) by which type of T cells. Experimental …
Immunotherapy for Brain Tumors: Where We Have Been, and Where Do We Go From Here?
AF Wang, B Hsueh, BD Choi, ER Gerstner… - … Treatment Options in …, 2024 - Springer
Opinion statement Immunotherapy for glioblastoma (GBM) remains an intensive area of
investigation. Given the seismic impact of cancer immunotherapy across a range of …
investigation. Given the seismic impact of cancer immunotherapy across a range of …
Non-invasive tracking of T cell recruitment to the tumor microenvironment in a murine glioma model by high field cellular magnetic resonance imaging
J Hunger - 2023 - archiv.ub.uni-heidelberg.de
Gliomas are characterized by increased T cell exhaustion and poor T cell infiltration into the
tumor as well as an overall highly immunosuppressive tumor microenvironment (TME) …
tumor as well as an overall highly immunosuppressive tumor microenvironment (TME) …