Poly (glutamic acid): Production, composites, and medical applications of the next-generation biopolymer
Numerous biopolymer-based functional composites have been developed for medical
applications. Poly (glutamic acid)(PGA) is an amino acid biopolymer that has recently …
applications. Poly (glutamic acid)(PGA) is an amino acid biopolymer that has recently …
[HTML][HTML] Delivery strategies of amphotericin B for invasive fungal infections
X Wang, IS Mohammad, L Fan, Z Zhao… - … Pharmaceutica Sinica B, 2021 - Elsevier
Invasive fungal infections (IFIs) represent a growing public concern for clinicians to manage
in many medical settings, with substantial associated morbidities and mortalities. Among …
in many medical settings, with substantial associated morbidities and mortalities. Among …
[HTML][HTML] Building a circular economy around poly (D/L-γ-glutamic acid)-a smart microbial biopolymer
M Parati, I Khalil, F Tchuenbou-Magaia… - Biotechnology …, 2022 - Elsevier
Bio-derived materials have long been harnessed for their potential as backbones of
biodegradable constructs. With increasing understanding of organismal biochemistry and …
biodegradable constructs. With increasing understanding of organismal biochemistry and …
Levan-based hydrogels for controlled release of Amphotericin B for dermal local antifungal therapy of Candidiasis
T Demirci, ME Hasköylü, MS Eroğlu… - European journal of …, 2020 - Elsevier
Hydrogels from Halomonas levan polysaccharide were prepared at different crosslinking
densities. Swelling results demonstrated pH dependent rather than temperature dependent …
densities. Swelling results demonstrated pH dependent rather than temperature dependent …
Husk-like zinc oxide nanoparticles induce apoptosis through ROS generation in epidermoid carcinoma cells: effect of incubation period on sol-gel synthesis and anti …
This study effectively reports the influence of experimental incubation period on the sol-gel
production of husk-like zinc oxide nanoparticles (ZNPs) and their anti-cancerous abilities …
production of husk-like zinc oxide nanoparticles (ZNPs) and their anti-cancerous abilities …
Biomimetically engineered Amphotericin B nano-aggregates circumvent toxicity constraints and treat systemic fungal infection in experimental animals
Biomimetic synthesis of nanoparticles offers a convenient and bio friendly approach to
fabricate complex structures with sub-nanometer precision from simple precursor …
fabricate complex structures with sub-nanometer precision from simple precursor …
In-silico approach as a tool for selection of excipients for safer amphotericin B nanoformulations
PA Todke, PV Devarajan - Journal of Controlled Release, 2022 - Elsevier
Safer and efficacious Amphotericin B (AmB) nanoformulations can be designed by
augmenting AmB in the monomeric or super-aggregated state, and restricting the …
augmenting AmB in the monomeric or super-aggregated state, and restricting the …
Recent advances in antifungal drug discovery based on polyene macrolide antibiotics
OA Omelchuk, AN Tevyashova… - Russian Chemical …, 2018 - iopscience.iop.org
The review summarizes recent advances in the synthesis of new derivatives of polyene
macrolide antibiotics by chemical modification and genetic engineering methods, results of …
macrolide antibiotics by chemical modification and genetic engineering methods, results of …
Development and anti-Candida evaluation of the vaginal delivery system of amphotericin B nanosuspension-loaded thermogel
Vulvovaginal candidiasis (VVC) is a typical kind of vaginal mucosal infection. Herein, we
developed a novel vaginal delivery system of amphotericin B (AmB) nanosuspension …
developed a novel vaginal delivery system of amphotericin B (AmB) nanosuspension …
Characterization and in vitro cytotoxic assessment of zinc oxide nano-particles in human epidermoid carcinoma cells
The study was designed to evaluate the effect of varying concentrations of ion-carriers on
the synthesis of zinc oxide nano-particles (ZONs). We also evaluated the anti-proliferative …
the synthesis of zinc oxide nano-particles (ZONs). We also evaluated the anti-proliferative …