Role of glutathione S-transferases in detoxification of a polycyclic aromatic hydrocarbon, methylcholanthrene
S Dasari, MS Ganjayi, P Yellanurkonda… - Chemico-biological …, 2018 - Elsevier
Abstract Glutathione S-transferases (GSTs), the versatile phase II biotransformation
enzymes, metabolize and detoxify a wide variety of toxic chemical compounds like …
enzymes, metabolize and detoxify a wide variety of toxic chemical compounds like …
[HTML][HTML] The glucosinolates: a sulphur glucoside family of mustard anti-tumour and antimicrobial phytochemicals of potential therapeutic application
J Melrose - Biomedicines, 2019 - mdpi.com
This study reviewed aspects of the biology of two members of the glucosinolate family,
namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties …
namely sinigrin and glucoraphanin and their anti-tumour and antimicrobial properties …
The susceptibility of humans to neurodegenerative and neurodevelopmental toxicities caused by organophosphorus pesticides
S Mostafalou, M Abdollahi - Archives of Toxicology, 2023 - Springer
The toxicology field is concerned with the impact of organophosphorus (OP) compounds on
human health. These compounds have been linked to an increased risk of neurological …
human health. These compounds have been linked to an increased risk of neurological …
Associations of short-term exposure to fine particulate matter with neural damage biomarkers: a panel study of healthy retired adults
J Song, R Qu, B Sun, R Chen, H Kan, Z An… - Environmental …, 2021 - ACS Publications
Exposure to fine particulate matter (PM2. 5) is associated with various adverse health
effects, such as respiratory and cardiovascular diseases. This study aimed to evaluate the …
effects, such as respiratory and cardiovascular diseases. This study aimed to evaluate the …
[HTML][HTML] Genetic polymorphisms in oxidative stress and inflammatory pathways as potential biomarkers in Alzheimer's disease and dementia
D Vogrinc, M Gregorič Kramberger, A Emeršič… - Antioxidants, 2023 - mdpi.com
Oxidative stress and neuroinflammation are important processes involved in Alzheimer's
disease (AD) and mild cognitive impairment (MCI). Numerous risk factors, including genetic …
disease (AD) and mild cognitive impairment (MCI). Numerous risk factors, including genetic …
Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort
I Zalachoras, E Ramos-Fernández, F Hollis, L Trovo… - Elife, 2022 - elifesciences.org
Emerging evidence is implicating mitochondrial function and metabolism in the nucleus
accumbens in motivated performance. However, the brain is vulnerable to excessive …
accumbens in motivated performance. However, the brain is vulnerable to excessive …
Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes
N Deng, YY Wu, Y Feng, WC Hsieh… - Proceedings of the …, 2022 - National Acad Sciences
Earlier work has shown that siRNA-mediated reduction of the SUPT4H or SUPT5H proteins,
which interact to form the DSIF complex and facilitate transcript elongation by RNA …
which interact to form the DSIF complex and facilitate transcript elongation by RNA …
Exposure to nickel chloride induces epigenetic modification on detoxification enzyme glutathione S‐transferase M2
YT Kang, WJ Yang, HC Huang… - Environmental …, 2024 - Wiley Online Library
Nickel (Ni) is a human carcinogen with genotoxic and epigenotoxic effects. Environmental
and occupational exposure to Ni increases the risk of cancer and chronic inflammatory …
and occupational exposure to Ni increases the risk of cancer and chronic inflammatory …
50-bp insertion/deletion polymorphism of the superoxide dismutase-1 is associated with bladder cancer risk in an Iranian population
S Sarabandi, H Effatpanah, N Sereshki… - … Nucleotides & Nucleic …, 2022 - Taylor & Francis
Bladder cancer (BC) is considered the sixth prevalent malignancy in men and the ninth
leading cause of malignancy-related worldwide. Superoxide dismutase (SOD) is an …
leading cause of malignancy-related worldwide. Superoxide dismutase (SOD) is an …
Antidepressant effect and modulation of the redox system mediated by tannic acid on lipopolysaccharide-induced depressive and inflammatory changes in mice
KP Luduvico, L Spohr, MSP Soares, FC Teixeira… - Neurochemical …, 2020 - Springer
Depression is an emotional disorder that causes mental and physical changes, and has
limited pharmacotherapy. Tannic acid (TA) is a polyphenol with previously described …
limited pharmacotherapy. Tannic acid (TA) is a polyphenol with previously described …