[HTML][HTML] Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

C Stillhart, K Vučićević, P Augustijns, AW Basit… - European Journal of …, 2020 - Elsevier
The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

HIV-1 integrase inhibitors: a comparative review of efficacy and safety

KK Scarsi, JP Havens, AT Podany, SN Avedissian… - Drugs, 2020 - Springer
The newest class of antiretrovirals for all persons living with HIV are the integrase strand
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …

Update on adverse effects of HIV integrase inhibitors

A Kolakowska, AF Maresca, IJ Collins… - Current treatment options …, 2019 - Springer
Purpose of review The goal of this paper is to provide an up-to-date review of adverse
events related to the class of integrase strand transfer inhibitors (INSTIs), which became the …

Evaluating cabotegravir/rilpivirine long-acting, injectable in the treatment of HIV infection: emerging data and therapeutic potential

C Fernandez, CL van Halsema - HIV/AIDS-Research and Palliative …, 2019 - Taylor & Francis
Cabotegravir and rilpivirine long-acting injectable antiretroviral therapy for the treatment of
HIV-1 infection brings promise of a new mode of delivery and potential solutions to some …

[HTML][HTML] HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity

L Cerveny, P Murthi, F Staud - … et Biophysica Acta (BBA)-Molecular Basis of …, 2021 - Elsevier
An estimated 1.3 million pregnant women were living with HIV in 2018. HIV infection is
associated with adverse pregnancy outcomes and all HIV-positive pregnant women …

Comparative clinical pharmacokinetics and pharmacodynamics of HIV-1 integrase strand transfer inhibitors: an updated review

AT Podany, KK Scarsi, MM Pham, CV Fletcher - Clinical pharmacokinetics, 2020 - Springer
Abstract Bictegravir, cabotegravir, dolutegravir, elvitegravir, and raltegravir are members of
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …

HIV-1 integrase strand transfer inhibitors and neurodevelopment

EG Foster, HE Gendelman, AN Bade - Pharmaceuticals, 2022 - mdpi.com
Children born to mothers, with or at risk, of human immunodeficiency virus type-1 (HIV-1)
infection are on the rise due to affordable access of antiretroviral therapy (ART) to pregnant …

Prevention of the Vertical Transmission of HIV; A Recap of the Journey so Far

MC Cardenas, S Farnan, BL Hamel, MC Mejia Plazas… - Viruses, 2023 - mdpi.com
In 1989, one in four (25%) infants born to women living with HIV were infected; by the age of
2 years, there was 25% mortality among them due to HIV. These and other pieces of data …

Cabotegravir, the Long-Acting Integrase Strand Transfer Inhibitor, Potently Inhibits Human T-Cell Lymphotropic Virus Type 1 Transmission in vitro

BS Schneiderman, MS Barski, GN Maertens - Frontiers in Medicine, 2022 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) is a deltaretrovirus most prevalent in
southwestern Japan, sub-Saharan Africa, Australia, South America, and the Caribbean …

Inhibition of HTLV-1 infection by HIV-1 first-and second-generation integrase strand transfer inhibitors

MS Barski, JJ Minnell, GN Maertens - Frontiers in Microbiology, 2019 - frontiersin.org
More than 10 million people worldwide are infected with the retrovirus human T-cell
lymphotropic virus type 1 (HTLV-1). Infection phenotypes can range from asymptomatic to …