Protein-based nanoparticles: From preparation to encapsulation of active molecules

M Tarhini, H Greige-Gerges, A Elaissari - International journal of …, 2017 - Elsevier
Nowadays, nanotechnology has become very integrated in the domain of pharmaceutical
sciences since nanoparticle dispersions show various advantages as drug carriers. Among …

[HTML][HTML] Fruit cuticular waxes as a source of biologically active triterpenoids

A Szakiel, C Pączkowski, F Pensec, C Bertsch - Phytochemistry Reviews, 2012 - Springer
The health benefits associated with a diet rich in fruit and vegetables include reduction of the
risk of chronic diseases such as cardiovascular disease, diabetes and cancer, that are …

The gastrointestinal behavior of saponins and its significance for their bioavailability and bioactivities

JN del Hierro, T Herrera, T Fornari, G Reglero… - Journal of Functional …, 2018 - Elsevier
Saponins are bioactive compounds of increasing interest. The events that take place during
digestion are highly related to their bioactivities, because saponins are poorly absorbed and …

Niosome encapsulation of curcumin: characterization and cytotoxic effect on ovarian cancer cells

YQ Xu, WR Chen, JK Tsosie, X Xie, P Li… - Journal of …, 2016 - Wiley Online Library
Curcumin, a natural chemical compound found in Curcuma longa, has been applied in
multiple medicinal areas from antibiotic to antitumor treatment. However, the chemical …

Oleanolic acid and related triterpenoids from olives on vascular function: Molecular mechanisms and therapeutic perspectives

R Rodriguez-Rodriguez - Current medicinal chemistry, 2015 - ingentaconnect.com
Oleanolic acid and related triterpenoids from olives modulate different signaling pathways,
showing a wide range of pharmacological activities against inflammation, cancer or …

Nanopharmaceutics: phytochemical-based controlled or sustained drug-delivery systems for cancer treatment

R Jeetah, A Bhaw-Luximon… - Journal of biomedical …, 2014 - ingentaconnect.com
This review is an attempt to assess the different classes of phytochemicals and some of their
members which have been encapsulated into nanocarrier systems for their …

Oleanolic acid protects against mast cell-mediated allergic responses by suppressing Akt/NF-κB and STAT1 activation

YM Kang, M Lee, HJ An - Phytomedicine, 2021 - Elsevier
Background Oleanolic acid (OA) is an active compound found in a variety of medicinal herbs
and plants. Though OA has been widely attributed with a variety of biological activities …

Advances on the anti-inflammatory activity of oleanolic acid and derivatives

X Zhang, H Wang, Y Xu, M Luan… - Mini Reviews in …, 2021 - ingentaconnect.com
Oleanolic acid can inhibit edema and exhibit obvious inhibitory activity to inflammatory by
activating of the pituitary-adrenal cortical system, inhibiting the synthesis or release of PGs …

[HTML][HTML] Liposomal co-delivered oleanolic acid attenuates doxorubicin-induced multi-organ toxicity in hepatocellular carcinoma

M Sarfraz, A Afzal, SM Raza, S Bashir, A Madni… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Doxorubicin in combination with other cytotoxic drugs has clinical advantages. However,
doxorubicin-induced cardiotoxicity negatively impacts clinical utility and outcomes …

Oleanolic acid loaded PEGylated PLA and PLGA nanoparticles with enhanced cytotoxic activity against cancer cells

DKW Man, L Casettari, M Cespi… - Molecular …, 2015 - ACS Publications
Oleanolic acid (OA) is a natural triterpenoid with anticancer properties, but its hydrophobic
nature and poor aqueous solubility pose challenges in pharmaceutical formulation …