Supergenes are genomic regions containing sets of tightly linked loci that control multi-trait
phenotypic polymorphisms under balancing selection. Recent advances in genomics have …

The recent advances in DNA sequencing technology are enabling a rapid increase in the
number of genomes being sequenced. However, many fundamental questions in genome …

Long nanopore reads are advantageous in de novo genome assembly. However, nanopore
reads usually have broad error distribution and high-error-rate subsequences. Existing error …

The prevalence of highly repetitive sequences within the human Y chromosome has
prevented its complete assembly to date and led to its systematic omission from genomic …

The genomics revolution has led to the sequencing of a large variety of nonmodel
organisms often referred to as “whole” or “complete” genome assemblies. But how complete …

Assembly of a complete Y chromosome is a significant challenge in animals with an XX/XY
sex-determination system. Recently, we created YY-supermale yellow catfish by crossing XY …

The eukaryotic genome is packaged into transcriptionally active euchromatin and silent
heterochromatin, with most studies focused on the former encompassing the majority of …

Repetitive DNA is a major organizational component of eukaryotic genomes, being
intrinsically related with their architecture and evolution. Tandemly repeated satellite DNAs …

Infectious outbreaks are the foremost global public health concern, challenging the current
healthcare system, which claims millions of lives annually. The most crucial way to control …

Summary The Human Genome Project opened an era of (epi) genomic research, and also
provided a platform for the development of new sequencing technologies. During and after …