Recent Advances in Strategies for Activation and Discovery/Characterization of Cryptic Biosynthetic Gene Clusters in Streptomyces
Streptomyces spp. are prolific sources of valuable natural products (NPs) that are of great
interest in pharmaceutical industries such as antibiotics, anticancer chemotherapeutics …
interest in pharmaceutical industries such as antibiotics, anticancer chemotherapeutics …
Recent Advances in Exploration and Biotechnological Production of Bioactive Compounds in Three Cyanobacterial Genera: Nostoc, Lyngbya, and Microcystis
Cyanobacteria, are only Gram-negative bacteria with the capacity of oxygenic
photosynthesis, so termed as “Cyanophyta” or “blue-green algae.” Their habitat is …
photosynthesis, so termed as “Cyanophyta” or “blue-green algae.” Their habitat is …
Insights into Streptomyces spp. isolated from the rhizospheric soil of Panax notoginseng: isolation, antimicrobial activity and biosynthetic potential for polyketides and …
F Peng, MY Zhang, SY Hou, J Chen, YY Wu… - BMC microbiology, 2020 - Springer
Background Streptomycetes from the rhizospheric soils are a rich resource of novel
secondary metabolites with various biological activities. However, there is still little …
secondary metabolites with various biological activities. However, there is still little …
Bioactive molecules from Nocardia: diversity, bioactivities and biosynthesis
Nocardia spp. are catalase positive, aerobic, and non-motile Gram-positive filamentous
bacteria. Many Nocarida spp. have been reported as unusual causes of diverse clinical …
bacteria. Many Nocarida spp. have been reported as unusual causes of diverse clinical …
Indispensable role of microbes in anticancer drugs and discovery trends
Recent years have seen an increased focus on the advancement of naturally derived
products for the treatment of cancer. Since the beginning of recorded history, nature has …
products for the treatment of cancer. Since the beginning of recorded history, nature has …
Identification and enhancing production of a novel macrolide compound in engineered Streptomyces peucetius
Streptomyces peucetius produces doxorubicin and daunorubicin, which are important
anticancer drugs. In this study, we activate peucemycin, a new antibacterial compound …
anticancer drugs. In this study, we activate peucemycin, a new antibacterial compound …
Biosynthetic pathway of peucemycin and identification of its derivative from Streptomyces peucetius
Streptomyces peucetius ATCC 27952 is a well-known producer of important anticancer
compounds, daunorubicin and doxorubicin. In this study, we successfully identified a new …
compounds, daunorubicin and doxorubicin. In this study, we successfully identified a new …
Production of a Novel Tetrahydroxynaphthalene (THN) Derivative from Nocardia sp. CS682 by Metabolic Engineering and Its Bioactivities
Nargenicin A1 is major secondary metabolite produced by Nocardia sp. CS682, with an
effective antibacterial activity against various Gram-positive bacteria. Most Nocardia spp …
effective antibacterial activity against various Gram-positive bacteria. Most Nocardia spp …
Genome mining of Streptomyces xinghaiensis NRRL B-24674T for the discovery of the gene cluster involved in anticomplement activities and detection of novel …
LY Chen, XQ Wang, YM Wang, X Geng, XN Xu… - Applied microbiology …, 2018 - Springer
Marine actinobacterium Streptomyces xinghaiensis NRRL B-24674 T has been
characterized as a novel species, but thus far, its biosynthetic potential remains unexplored …
characterized as a novel species, but thus far, its biosynthetic potential remains unexplored …
Genomic and Metabolite Profiling Reveal a Novel Streptomyces Strain, QHH-9511, from the Qinghai-Tibet Plateau
XL Feng, RQ Zhang, DC Wang, WG Dong… - Microbiology …, 2023 - Am Soc Microbiol
The prevalence of superbugs, represented by methicillin-resistant Staphylococcus aureus
(MRSA), has become a serious clinical and public safety concern with rising incidence in …
(MRSA), has become a serious clinical and public safety concern with rising incidence in …