Purpose of review Antibody-mediated rejection is the leading cause of deterioration of graft
function and graft loss after kidney transplantation. Recent studies have reported an …

Atherosclerosis (AS) is a serious threat to the cardiovascular system. Circular RNA
circ_0003645 was found to be differentially expressed in the process of AS. Our study tried …

Background/Aims: This study aimed to analyze the impact of microRNA-499 (miR-499) on
the inflammatory damage of endothelial cells during coronary artery disease (CAD) via the …

Background Hypoxia contributes to a cascade of inflammatory response mechanisms in
kidneys that result in the development of renal interstitial fibrosis and subsequent chronic …

Abstract Background/Aims: Vascular relaxation caused by Triiodothyronine (T3) involves
direct activation of endothelial cells (EC) and vascular smooth muscle cells (VSMC) …

Background/Aims: The mechanistic target of rapamycin (mTOR) signaling pathway is
essential for angiogenesis and embryonic development. DEP domain-containing mTOR …

Endothelial cell apoptosis plays an important role in the pathophysiological mechanism of
vascular complications in type 2 diabetes mellitus (T2DM). Argirein, a new synthetic …

Background/Aims: Endothelin-1 is implicated in the pathogenesis of hypertension, but the
underlying mechanisms remained elusive. Our previous study found that inhibition of …

Abstract Superoxide anion (O 2.-), as the first generated reactive oxygen species (ROS), has
been considered to be highly deleterious to cell functions. The measurement of intracellular …

Allograft loss remains a severe clinical problem after kidney transplantation. The molecular
mechanism of graft loss is a complex process involving T and/or B cell activation …