Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

ABSTRACT PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) constitute a
small RNA-based adaptive immune system that restricts the deleterious activity of mobile …

In eukaryotes, small RNA guides, such as small interfering RNAs and microRNAs, direct
AGO-clade Argonaute proteins to regulate gene expression and defend the genome against …

The piRNA pathway is a highly conserved mechanism to repress transposable element (TE)
activity in the animal germline via a specialized class of small RNAs called piwi-interacting …

PIWI-interacting RNAs (piRNAs) are responsible for preventing the movement of
transposable elements in germ cells and protect the integrity of germline genomes. In this …

During evolution, several types of sequences pass through genomes. Along with mutations
and internal genetic tinkering, they are a useful source of genetic variability for adaptation …

Unique to animals, PIWI-interacting RNAs (piRNAs) defend organisms against threats to
germline integrity evoked by transposons, retroviruses, and inappropriate expression of …

Murine neural stem cells (NSCs) were recently shown to release piRNA-containing
exosomes/microvesicles (Ex/Mv) for exerting antiviral immunity, but it remains unknown if …

Argonautes are small RNA-binding proteins, with some having small RNA-guided
endonuclease (slicer) activity that cleaves target nucleic acids. One cardinal rule that is …

PIWI-interacting RNAs (piRNA) suppress selfish genetic elements and are essential for germ
cell biology in animals. They also play critical roles in regeneration in planaria, regulate …