Aza-2'-deoxycytidine (AzaD), also known as Decitabine, is a deoxycytidine analog that is
typically used to activate methylated and silenced genes by promoter demethylation …

Calponin and transgelin (originally named SM22) are homologous cytoskeleton proteins
that regulate actin-activated myosin motor functions in smooth muscle contraction and non …

Background Metastatic bladder cancer (BLCA) is a lethal disease with an unmet need for
study. Transgelin (TAGLN) is an actin-binding protein that affects the dynamics of the actin …

Background Triple-negative breast cancer (TNBC) constitutes 10–20% of breast cancers
and is challenging to treat due to a lack of effective targeted therapies. Previous studies in …

Mass spectrometry (MS)-based microproteomics on localized regions of tissue sections was
achieved by direct coupling of liquid microjunction microextraction with a nanoscale liquid …

Using bioinformatics analysis, we found some mature human miRNAs containing G-rich
sequences with four G-tracts that had a high probability of forming G-quadruplex structures …

Background: BRCA1 and RASSF1A promoter methylation has been reported to be
correlated with a worse survival in patients with breast cancer. However, the prognostic …

Background Metabolic syndrome is a risk factor for type 2 diabetes and cardiovascular
disease. We identified common genetic variants that alter the risk for metabolic syndrome in …

Bone metastasis (BM) is one of the main manifestations of advanced breast cancer (BC),
causing complications such as pathological fractures, which seriously affects the quality of …

A significant proportion of patients with elevated LDL and a clinical presentation of familial
hypercholesterolemia do not carry known genetic mutations associated with …