[HTML][HTML] Male oxidative stress infertility (MOSI): proposed terminology and clinical practice guidelines for management of idiopathic male infertility

A Agarwal, N Parekh, MKP Selvam… - The world journal of …, 2019 - synapse.koreamed.org
Despite advances in the field of male reproductive health, idiopathic male infertility, in which
a man has altered semen characteristics without an identifiable cause and there is no …

Paternal obesity negatively affects male fertility and assisted reproduction outcomes: a systematic review and meta-analysis

JM Campbell, M Lane, JA Owens, HW Bakos - Reproductive biomedicine …, 2015 - Elsevier
This systematic review investigated the effect of paternal obesity on reproductive potential.
Databases searched were Pubmed, Ovid, Web of Science, Scopus, Cinahl and Embase …

Novel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentation

CL Cho, SC Esteves, A Agarwal - Asian Journal of Andrology, 2016 - journals.lww.com
Varicocele has been associated with reduced male reproductive potential. With the
advances in biomolecular techniques, it has been possible to better understand the …

Relationship between varicocele and sperm DNA damage and the effect of varicocele repair: a meta-analysis

YJ Wang, RQ Zhang, YJ Lin, RG Zhang… - Reproductive biomedicine …, 2012 - Elsevier
Varicocele, a cause of male infertility, occurs in nearly 40% of infertile males. It has been
postulated that varicoceles may cause sperm DNA damage. Sperm DNA integrity has been …

Oxidation-reduction potential of semen: what is its role in the treatment of male infertility?

A Agarwal, S Roychoudhury… - … Advances in Urology, 2016 - journals.sagepub.com
The diagnosis of male infertility relies largely on conventional semen analysis, and its
interpretation has a profound influence on subsequent management of patients. Despite …

Diet and exercise in an obese mouse fed a high-fat diet improve metabolic health and reverse perturbed sperm function

NO Palmer, HW Bakos, JA Owens… - American Journal …, 2012 - journals.physiology.org
Male obesity is associated with reduced sperm motility and morphology and increased
sperm DNA damage and oxidative stress; however, the reversibility of these phenotypes has …

The hypoxic testicle: physiology and pathophysiology

JG Reyes, JG Farias… - Oxidative Medicine …, 2012 - Wiley Online Library
Mammalian spermatogenesis is a complex biological process occurring in the seminiferous
tubules in the testis. This process represents a delicate balance between cell proliferation …

[HTML][HTML] Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

FTL Neto, M Roque, SC Esteves - Fertility and sterility, 2021 - Elsevier
Objective To evaluate the effect of varicocelectomy on sperm deoxyribonucleic acid
fragmentation (SDF) rates in infertile men with clinical varicocele. Design Systematic review …

[HTML][HTML] Are varicoceles associated with increased deoxyribonucleic acid fragmentation?

A Zini, G Dohle - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To perform a literature search on the association between varicocele and
sperm DNA fragmentation. DESIGN: Systematic review. PATIENT (S): Men with a varicocele …

Insight into oxidative stress in varicocele-associated male infertility: part 2

A Hamada, SC Esteves, A Agarwal - Nature Reviews Urology, 2013 - nature.com
Varicocele, the leading cause of male infertility, can impair spermatogenesis through several
pathophysiological mechanisms. Of these, current evidence suggests that oxidative stress is …