Fundamentals and methods for T‐and B‐cell epitope prediction
JL Sanchez-Trincado… - Journal of …, 2017 - Wiley Online Library
Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …
developing pathogen‐specific memory that confers immunological protection. Memory and …
Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes
Antibodies have become an indispensable tool for many biotechnological and clinical
applications. They bind their molecular target (antigen) by recognizing a portion of its …
applications. They bind their molecular target (antigen) by recognizing a portion of its …
BepiPred‐3.0: Improved B‐cell epitope prediction using protein language models
B‐cell epitope prediction tools are of great medical and commercial interest due to their
practical applications in vaccine development and disease diagnostics. The introduction of …
practical applications in vaccine development and disease diagnostics. The introduction of …
Maxout networks
We consider the problem of designing models to leverage a recently introduced
approximate model averaging technique called dropout. We define a simple new model …
approximate model averaging technique called dropout. We define a simple new model …
Machine learning for biologics: opportunities for protein engineering, developability, and formulation
Successful biologics must satisfy multiple properties including activity and particular
physicochemical features that are globally defined as developability. These multiple …
physicochemical features that are globally defined as developability. These multiple …
An introduction to B‐cell epitope mapping and in silico epitope prediction
L Potocnakova, M Bhide… - Journal of immunology …, 2016 - Wiley Online Library
Identification of B‐cell epitopes is a fundamental step for development of epitope‐based
vaccines, therapeutic antibodies, and diagnostic tools. Epitope‐based antibodies are …
vaccines, therapeutic antibodies, and diagnostic tools. Epitope‐based antibodies are …
Comprehensive serological profiling of human populations using a synthetic human virome
Introduction The collection of viruses found to infect humans can have profound effects on
human health. In addition to directly causing acute or chronic illness, viral infection can alter …
human health. In addition to directly causing acute or chronic illness, viral infection can alter …
[HTML][HTML] iBCE-EL: a new ensemble learning framework for improved linear B-cell epitope prediction
Identification of B-cell epitopes (BCEs) is a fundamental step for epitope-based vaccine
development, antibody production, and disease prevention and diagnosis. Due to the …
development, antibody production, and disease prevention and diagnosis. Due to the …
Retrieval and investigation of data on SARS-CoV-2 and COVID-19 using bioinformatics approach
Sudden emergence and a rapid outbreak of SARS-CoV-2 accompanied by a devastating
impact on the economy and public health has driven extensive scientific mobilization to …
impact on the economy and public health has driven extensive scientific mobilization to …