Neuroplastic changes following brain ischemia and their contribution to stroke recovery: novel approaches in neurorehabilitation
Ischemic damage to the brain triggers substantial reorganization of spared areas and
pathways, which is associated with limited, spontaneous restoration of function. A better …
pathways, which is associated with limited, spontaneous restoration of function. A better …
Filling the gaps on stroke research: Focus on inflammation and immunity
D Levard, I Buendia, A Lanquetin, M Glavan… - Brain, behavior, and …, 2021 - Elsevier
For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …
Short-chain fatty acids improve poststroke recovery via immunological mechanisms
R Sadler, JV Cramer, S Heindl, S Kostidis… - Journal of …, 2020 - Soc Neuroscience
Recovery after stroke is a multicellular process encompassing neurons, resident immune
cells, and brain-invading cells. Stroke alters the gut microbiome, which in turn has …
cells, and brain-invading cells. Stroke alters the gut microbiome, which in turn has …
Advanced neurotechnologies for the restoration of motor function
Stroke is one of the leading causes of long-term disability. Advanced technological solutions
(" neurotechnologies") exploiting robotic systems and electrodes that stimulate the nervous …
(" neurotechnologies") exploiting robotic systems and electrodes that stimulate the nervous …
Task-specific modulation of corticospinal neuron activity during motor learning in mice
N Serradj, F Marino, Y Moreno-López… - Nature …, 2023 - nature.com
Motor skill learning relies on the plasticity of the primary motor cortex as task acquisition
drives cortical motor network remodeling. Large-scale cortical remodeling of evoked motor …
drives cortical motor network remodeling. Large-scale cortical remodeling of evoked motor …
Cortical transplantation of brain‐mimetic glycosaminoglycan scaffolds and neural progenitor cells promotes vascular regeneration and functional recovery after …
MR McCrary, K Jesson, ZZ Wei… - Advanced …, 2020 - Wiley Online Library
Stroke causes significant mortality and morbidity. Currently, there are no treatments which
can regenerate brain tissue lost to infarction. Neural progenitor cells (NPCs) are at the …
can regenerate brain tissue lost to infarction. Neural progenitor cells (NPCs) are at the …
Artery targeted photothrombosis widens the vascular penumbra, instigates peri-infarct neovascularization and models forelimb impairments
TA Clark, C Sullender, SM Kazmi, BL Speetles… - Scientific reports, 2019 - nature.com
The photothrombotic stroke model generates localized and reproducible ischemic infarcts
that are useful for studying recovery mechanisms, but its failure to produce a substantial …
that are useful for studying recovery mechanisms, but its failure to produce a substantial …
Automated home cage training of mice in a hold-still center-out reach task
An obstacle to understanding neural mechanisms of movement is the complex, distributed
nature of the mammalian motor system. Here we present a novel behavioral paradigm for …
nature of the mammalian motor system. Here we present a novel behavioral paradigm for …
The tactile experience paired with vagus nerve stimulation determines the degree of sensory recovery after chronic nerve damage
Loss of sensory function is a common consequence of neurological injury. Recent clinical
and preclinical evidence indicates vagus nerve stimulation (VNS) paired with tactile …
and preclinical evidence indicates vagus nerve stimulation (VNS) paired with tactile …
High-throughput automatic training system for odor-based learned behaviors in head-fixed mice
Understanding neuronal mechanisms of learned behaviors requires efficient behavioral
assays. We designed a high-throughput automatic training system (HATS) for olfactory …
assays. We designed a high-throughput automatic training system (HATS) for olfactory …