Nuclear Receptors-Mediated Endocrine Disrupting Effects of Non-Phthalate Plasticizers: A Review

J Yu, H Zou, T Zhang, J Zhang - Journal of Agricultural and Food …, 2023 - ACS Publications
In 2021, the global market for non-phthalate plasticizers reached $3.1 billion, and it is
projected to grow by 25.8% by 2025. These plasticizers have gained substantial attention as …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways

H Mohammadi, S Ashari - Environmental Science and Pollution Research, 2021 - Springer
The wide use of phthalates, as phthalates are used in the manufacturing of not only plastics
but also many others goods, has become a main concern in the current century because of …

Adipogenic activity of chemicals used in plastic consumer products

J Völker, F Ashcroft, Å Vedøy… - … science & technology, 2022 - ACS Publications
Bisphenols and phthalates, chemicals frequently used in plastic products, promote obesity in
cell and animal models. However, these well-known metabolism-disrupting chemicals …

Postnatal exposure to DINP was associated with greater alterations of lipidomic markers for hepatic steatosis than DEHP in postweaning mice

Y Yang, F Sun, H Chen, H Tan, L Yang, L Zhang… - Science of the Total …, 2021 - Elsevier
The toxicity of the endocrine disruptor di (2-ethylhexyl) phthalate (DEHP) has been
extensively studied for its hormonal dysregulation, obesogenic effect and associated …

[HTML][HTML] Concentrations and endocrine disruptive potential of phthalates in marine mammals from the Norwegian Arctic

H Routti, M Harju, K Lühmann, J Aars, A Ask… - Environment …, 2021 - Elsevier
This study investigated concentrations of phthalates (diesters of phthalic acids) in
blubber/adipose tissue of blue whales (Balaenoptera musculus), fin whales (Balaenoptera …

6: 2 Cl-PFESA has the potential to cause liver damage and induce lipid metabolism disorders in female mice through the action of PPAR-γ

Z Pan, W Miao, C Wang, W Tu, C Jin, Y Jin - Environmental Pollution, 2021 - Elsevier
2 Cl-PFESA is a polyfluoroalkyl ether with high environmental persistence that has been
confirmed to have significant adverse effects on animals. In this study, 6-week-old female …

Microplastics and their associated organic pollutants from the coastal waters of the central Adriatic Sea (Italy): Investigation of adipogenic effects in vitro

M Capriotti, P Cocci, L Bracchetti, E Cottone… - Chemosphere, 2021 - Elsevier
Highlights•Floating MPs were collected along the western coasts of the Central Adriatic
Sea.•MPs were found in all sampling stations showing the highest abundance in open …

Midpregnancy Phthalate and Phenol Biomarkers in Relation to Infant Body Composition: The Healthy Start Prospective Cohort

DR Stevens, AP Starling, PA Bommarito… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Gestational phthalate and phenol exposure disrupts adipogenesis, contributing
to obesity in mice. Whether gestational phthalate or phenol exposure is associated with …

PPARγ as a potential target for adipogenesis induced by fine particulate matter in 3T3-L1 Preadipocytes

Y Cao, Y Chen, K Miao, S Zhang, F Deng… - Environmental …, 2023 - ACS Publications
Mounting evidence has shown that ambient PM2. 5 exposure is closely associated with the
development of obesity, and adipose tissue represents an important endocrine target for …