Triazole hybrid compounds: A new frontier in malaria treatment
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …
compounds stands out as a groundbreaking development. Combining the advantages of …
Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond
Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …
Recent developments in antimalarial activities of 4-aminoquinoline derivatives
Malaria is the fifth most lethal parasitic infection in the world. Antimalarial medications have
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …
Metal complexes derived from bidentate ligands: Synthesis, catalytic and biological applications
DI Ugwu, J Conradie - Inorganica Chimica Acta, 2023 - Elsevier
This review focusses on metal complexes containing bidentate ligands. The development in
the synthesis and some applications of these complexes, reported mainly in the last two …
the synthesis and some applications of these complexes, reported mainly in the last two …
Antimalarial Agents Derived from Metal‐Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle
L Colina‐Vegas, M da Cruz B. Silva… - … A European Journal, 2023 - Wiley Online Library
Malaria is the one of the deadliest infectious diseases worldwide. Chemically, quinolines are
excellent ligands for metal coordination and are deployed as drugs for malaria treatment …
excellent ligands for metal coordination and are deployed as drugs for malaria treatment …
Antimicrobial Activity of Rhenium Di- and Tricarbonyl Diimine Complexes: Insights on Membrane-Bound S. aureus Protein Binding
Antimicrobial resistance is one of the major human health threats, with significant impacts on
the global economy. Antibiotics are becoming increasingly ineffective as drug-resistance …
the global economy. Antibiotics are becoming increasingly ineffective as drug-resistance …
Exploring the in vitro anticancer activities of Re (I) picolinic acid and its fluorinated complex derivatives on lung cancer cells: a structural study
Fifteen rhenium (I) tricarbonyl complexes of the form fac-[Re (N, O')(CO) 3 (X)], where N, O'-
bidentate ligand= 2-picolinic acid (Pico); 3, 5-difluoropyridine-2-carboxylic acid (Dfpc); 3 …
bidentate ligand= 2-picolinic acid (Pico); 3, 5-difluoropyridine-2-carboxylic acid (Dfpc); 3 …
Pyridine and Pyrimidine hybrids as privileged scaffolds in antimalarial drug discovery: A recent development
Malaria continues to pose a significant threat to global health, which is exacerbated by the
emergence of drug-resistant strains, necessitating the urgent development of new …
emergence of drug-resistant strains, necessitating the urgent development of new …
Exploring antimalarial potential: Conjugating organometallic moieties with organic fragments for enhanced efficacy
In the search for novel ligands with efficacy against various diseases, particularly parasitic
diseases, molecular hybridization of organometallic units into biologically active scaffolds …
diseases, molecular hybridization of organometallic units into biologically active scaffolds …
Tricarbonyl rhenium (i) complexes with 8-hydroxyquinolines: structural, chemical, antibacterial, and anticancer characteristics
K Łyczko, A Pogorzelska, U Częścik, M Koronkiewicz… - RSC …, 2024 - pubs.rsc.org
Twelve tricarbonyl rhenium (I) complexes in the '2+ 1'system with the anionic bidentate N, O-
donor ligand (deprotonated 8-hydroxyquinoline (HQ) or its 2-methyl (MeHQ) or 5-chloro …
donor ligand (deprotonated 8-hydroxyquinoline (HQ) or its 2-methyl (MeHQ) or 5-chloro …