Transcription factors (TFs) regulate gene programs, thereby controlling diverse cellular
processes and cell states. To comprehensively understand TFs and the programs they …

The Krüppel-like factors (KLFs) family of proteins control several key biological processes
that include proliferation, differentiation, metabolism, apoptosis and inflammation …

Specificity proteins (SPs) and Krüppel-like factors (KLFs) belong to the family of transcription
factors that contain conserved zinc finger domains involved in binding to target DNA …

The Krüppel-like factor and specificity protein (KLF/SP) genes play key roles in critical
biological processes including stem cell maintenance, cell proliferation, embryonic …

The liver performs a large number of essential synthetic and regulatory functions that are
acquired during fetal development and persist throughout life. Their disruption underlies a …

The zebrafish (Danio rerio) has been increasingly explored in pharmaceutical research as a
promising alternative model for toxicological screens. This necessitates a thorough …

Members of the Krüppel-like factor (KLF) family of transcription factors, which are
characterized by the presence of three conserved Cys2/His2 zinc-fingers in their C-terminal …

The liver acts as a central hub that controls several essential physiological processes
ranging from metabolism to detoxification of xenobiotics. At the cellular level, these …

The adult liver of most vertebrates is predominantly comprised of hepatocytes. However,
these cells must work in concert with biliary, stellate, vascular, and immune cells to …

Background and aims Great interest persists in useful therapeutic targets in glioblastoma
(GBM). Deregulation of microRNAs (mi RNA s) expression has been associated with cancer …