Peptides as a therapeutic strategy against Klebsiella pneumoniae
CM de Souza, ÁP da Silva, NGO Júnior… - Trends in …, 2022 - cell.com
Increasing levels of resistance to conventional antibiotics have led to a search for new
therapeutic options against bacterial infections. Klebsiella pneumoniae is considered a …
therapeutic options against bacterial infections. Klebsiella pneumoniae is considered a …
Antibacterial action mechanisms and mode of trypsin inhibitors: a systematic review
AM de Souza Nascimento… - Journal of Enzyme …, 2022 - Taylor & Francis
This systematic review (SR) aimed to gather studies describing the antibacterial action
mechanisms and mode of trypsin inhibitors. The review protocol was registered …
mechanisms and mode of trypsin inhibitors. The review protocol was registered …
[HTML][HTML] Prevention of hospital pathogen biofilm formation by antimicrobial peptide KWI18
LS Lima, SR Ramalho, GC Sandim, EB Parisotto… - Microbial …, 2022 - Elsevier
This study investigated the antimicrobial and antibiofilm activity of KWI18, a new synthetic
peptide. KWI18 was tested against planktonic cells and Pseudomonas aeruginosa and …
peptide. KWI18 was tested against planktonic cells and Pseudomonas aeruginosa and …
[HTML][HTML] A new bioinspired peptide on defensin from C. annuum fruits: Antimicrobial activity, mechanisms of action and therapeutical potential
Background Antimicrobial peptides, natural or synthetic, appear as promising molecules for
antimicrobial therapy because of their both broad antimicrobial activity and mechanism of …
antimicrobial therapy because of their both broad antimicrobial activity and mechanism of …
Potent Anti-Candida Fraction Isolated from Capsicum chinense Fruits Contains an Antimicrobial Peptide That is Similar to Plant Defensin and is Able to Inhibit the …
MCL Aguieiras, LM Resende, TAM Souza… - Probiotics and …, 2021 - Springer
Antimicrobial peptides (AMPs) are molecules present in several life forms, possess broad-
spectrum of inhibitory activity against pathogenic microorganisms, and are a promising …
spectrum of inhibitory activity against pathogenic microorganisms, and are a promising …
Prospecting in silico antibacterial activity of a peptide from trypsin inhibitor isolated from tamarind seed
GS Oliveira, AMS Nascimento, ABS Luz… - Journal of Enzyme …, 2023 - Taylor & Francis
Bacterial infections have become a global concern, stimulating the growing demand for
natural and biologically safe therapeutic agents with antibacterial action. This study was …
natural and biologically safe therapeutic agents with antibacterial action. This study was …
The synthetic antimicrobial peptide IKR18 displays anti-infectious properties in Galleria mellonella in vivo model
SR Ramalho, JCO Sardi, EC Júnior, R Marchetto… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Antimicrobial peptides (AMPs) are promising tools for developing new antibiotics. We
described the design of IKR18, an AMP designed with the aid of computational tools. IKR18 …
described the design of IKR18, an AMP designed with the aid of computational tools. IKR18 …
Plant Protease Inhibitors as Emerging Antimicrobial Peptide Agents: A Comprehensive Review
Antimicrobial peptides (AMPs) are important mediator molecules of the innate defense
mechanisms in a wide range of living organisms, including bacteria, mammals, and plants …
mechanisms in a wide range of living organisms, including bacteria, mammals, and plants …
Computer-made peptide RQ18 acts as a dual antifungal and antibiofilm peptide though membrane-associated mechanisms of action
CV Almeida, CFR de Oliveira… - Archives of Biochemistry …, 2024 - Elsevier
The spread of fungi resistant to conventional drugs has become a threatening problem. In
this context, antimicrobial peptides (AMPs) have been considered as one of the main …
this context, antimicrobial peptides (AMPs) have been considered as one of the main …
Boosting the antibacterial potential of a linear encrypted peptide in a Kunitz-type inhibitor (ApTI) through physicochemical-guided approaches
C de Oliveira Gutierrez, LH de Oliveira Almeida… - Biochimie, 2024 - Elsevier
Bacterial resistance has become a serious public health problem in recent years, thus
encouraging the search for new antimicrobial agents. Here, we report an antimicrobial …
encouraging the search for new antimicrobial agents. Here, we report an antimicrobial …