Roles of extracellular HSPs as biomarkers in immune surveillance and immune evasion

EA Taha, K Ono, T Eguchi - International Journal of Molecular Sciences, 2019 - mdpi.com
Extracellular heat shock proteins (ex-HSPs) have been found in exosomes, oncosomes,
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …

Autoimmune and inflammatory mechanisms in atherosclerosis

G Wick, M Knoflach, Q Xu - Annu. Rev. Immunol., 2004 - annualreviews.org
The present review focuses on the concept that cellular and humoral immunity to the
phylogenetically highly conserved antigen heat shock protein 60 (HSP60) is the initiating …

Complement in the homeostatic and ischemic brain

A Alawieh, A Elvington, S Tomlinson - Frontiers in immunology, 2015 - frontiersin.org
The complement system is a component of the immune system involved in both recognition
and response to pathogens, and it is implicated in an increasing number of homeostatic and …

Complement components, C3 and C4, and the metabolic syndrome

M Copenhaver, CY Yu, RP Hoffman - Current diabetes reviews, 2019 - ingentaconnect.com
Introduction: Increased systemic inflammation plays a significant role in the development of
adult cardiometabolic diseases such as insulin resistance, dyslipidemia, atherosclerosis …

MASPs at the crossroad between the complement and the coagulation cascades-the case for COVID-19

V Bumiller-Bini, C de Freitas Oliveira-Toré… - … and molecular biology, 2021 - SciELO Brasil
Components of the complement system and atypical parameters of coagulation were
reported in COVID-19 patients, as well as the exacerbation of the inflammation and …

The link of C4B null allele to autism and to a family history of autoimmunity in Egyptian autistic children

GA Mostafa, AA Shehab - Journal of neuroimmunology, 2010 - Elsevier
The reason behind the initiation of autoimmunity, which may have a role in autism, is not
well understood. There is an association between some autoimmune disorders and …

Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke

T Hiwasa, H Wang, K Goto, S Mine, T Machida… - BMC medicine, 2021 - Springer
Background Acute ischemic stroke (AIS) is a serious cause of mortality and disability. AIS is
a serious cause of mortality and disability. Early diagnosis of atherosclerosis, which is the …

Serum anti‐LRPAP1 is a common biomarker for digestive organ cancers and atherosclerotic diseases

M Sumazaki, H Shimada, M Ito, F Shiratori… - Cancer …, 2020 - Wiley Online Library
Some cancers are related to atherosclerotic diseases; therefore, these two types of disease
may share some antibody biomarkers in common. To investigate this, a first screening of …

Elevated levels of autoantibodies against DNAJC2 in sera of patients with atherosclerotic diseases

Y Yoshida, XM Zhang, H Wang, T Machida, S Mine… - Heliyon, 2020 - cell.com
Background Serum antibody markers have been increasingly identified not only for cancer
and autoimmune diseases but also for atherosclerosis-related diseases such as acute …

Relationship of anti-60 kDa heat shock protein and anti-cholesterol antibodies to cardiovascular events

A Veres, G Füst, M Smieja, M McQueen, A Horváth… - Circulation, 2002 - Am Heart Assoc
Background—Several recent studies have indicated an association between key
inflammatory mediators and atherosclerotic diseases. We evaluated whether high levels of …