Precision psychiatry and Research Domain Criteria: Implications for clinical trials and future practice

LM Williams, WT Carpenter, C Carretta… - CNS …, 2024 - cambridge.org
Psychiatric disorders are associated with significant social and economic burdens, many of
which are related to issues with current diagnosis and treatments. The coronavirus (COVID …

The dynamic interplay between puberty and structural brain development as a predictor of mental health difficulties in adolescence: A systematic review

S Kretzer, AJ Lawrence, R Pollard, X Ma, PJ Chen… - Biological …, 2024 - Elsevier
Puberty is a time of intense reorganization of brain structure and a high-risk period for the
onset of mental health problems, with variations in pubertal timing and tempo intensifying …

Developmental trajectories of irritability across the transition to toddlerhood: Associations with effortful control and psychopathology

Y Zhang, LA MacNeill, RC Edwards, JL Burns… - Research on Child and …, 2024 - Springer
Preschool-age irritability is a transdiagnostic marker of internalizing and externalizing
problems. However, researchers have generally been reluctant to examine irritability within …

Prevalence, stability, and predictive utility of the Multidimensional Assessment of Preschoolers Scales clinically optimized irritability score: Pragmatic early assessment …

JL Wiggins, A Ureña Rosario… - … Journal of Methods …, 2023 - Wiley Online Library
Objectives Characterizing the scope and import of early childhood irritability is essential for
real‐world actualization of this reliable indicator of transdiagnostic mental health risk. Thus …

Don't get lost in translation: Integrating developmental and implementation sciences to accelerate real-world impact on children's development, health, and wellbeing

LS Wakschlag, AL Finlay-Jones, LA MacNeill… - Frontiers in Public …, 2022 - frontiersin.org
Translation of developmental science discoveries is impeded by numerous barriers at
different stages of the research-to-practice pipeline. Actualization of the vast potential of the …

Predictive utility of irritability “in context”: Proof-of-principle for an early childhood mental health risk calculator

LS Wakschlag, LA MacNeill, LR Pool… - Journal of Clinical …, 2024 - Taylor & Francis
Objective We provide proof-of-principle for a mental health risk calculator advancing clinical
utility of the irritability construct for identification of young children at high risk for common …

Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum

G Michelini, CO Carlisi, NR Eaton, JT Elison… - World …, 2024 - Wiley Online Library
Features of autism spectrum disorder, attention‐deficit/hyperactivity disorder, learning
disorders, intellectual disabilities, and communication and motor disorders usually emerge …

Neurodevelopmental vulnerability to psychosis: developmentally-based methods enable detection of early life inhibitory control deficits that predict psychotic-like …

VC Zarubin, KSF Damme, T Vargas… - Psychological …, 2023 - cambridge.org
BackgroundInhibitory control develops in early childhood, and atypical development may be
a measurable marker of risk for the later development of psychosis. Additionally, inhibitory …

Principles, policies, and practices: Thoughts on their integration over the rise of the developmental psychopathology perspective and into the future

EB Tone, CC Henrich - Development and Psychopathology, 2024 - cambridge.org
Developmental psychopathology has, since the late 20th century, offered an influential
integrative framework for conceptualizing psychological health, distress, and dysfunction …

Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth

A Qiu, C Liu - Neuropsychopharmacology, 2023 - nature.com
Adolescence is a period of significant brain development and maturation, and it is a time
when many mental health problems first emerge. This study aimed to explore a …