Mitochondrial functionality in male fertility: from spermatogenesis to fertilization
Mitochondria are structurally and functionally distinct organelles that produce adenosine
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …
triphosphate (ATP) through oxidative phosphorylation (OXPHOS), to provide energy to …
Spermatogenesis in humans and its affecting factors
FTL Neto, PV Bach, BB Najari, PS Li… - Seminars in cell & …, 2016 - Elsevier
Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …
into spermatozoa requires the participation of several cell types, hormones, paracrine …
Bisphenol A (BPA) and cell signaling pathways
M Murata, JH Kang - Biotechnology advances, 2018 - Elsevier
Abstract Bisphenol A (BPA; 4, 4′-isopropylidenediphenol) is an endocrine disruptor that is
used as a material for the production of phenol resins, polyacrylates, polyesters, epoxy …
used as a material for the production of phenol resins, polyacrylates, polyesters, epoxy …
Mitochondria quality control and male fertility
Simple Summary Mitochondria play a crucial role in numerous cellular processes, including
energy production, apoptosis, and calcium homeostasis. In the male reproductive system …
energy production, apoptosis, and calcium homeostasis. In the male reproductive system …
Spermatogenesis
H Nishimura, SW L'Hernault - Current Biology, 2017 - cell.com
Most organisms consist of two cell lineages—somatic cells and germ cells. The former are
required for the current generation, and the latter create offspring. Male and female germ …
required for the current generation, and the latter create offspring. Male and female germ …
[HTML][HTML] Etiologies of sperm oxidative stress
P Sabeti, S Pourmasumi, T Rahiminia… - International Journal …, 2016 - ncbi.nlm.nih.gov
Sperm is particularly susceptible to reactive oxygen species (ROS) during critical phases of
spermiogenesis. However, the level of seminal ROS is restricted by seminal antioxidants …
spermiogenesis. However, the level of seminal ROS is restricted by seminal antioxidants …
Dichloroacetate and cancer: new home for an orphan drug?
S Kankotia, PW Stacpoole - Biochimica et Biophysica Acta (BBA)-Reviews …, 2014 - Elsevier
We reviewed the anti-cancer effects of DCA, an orphan drug long used as an investigational
treatment for various acquired and congenital disorders of mitochondrial intermediary …
treatment for various acquired and congenital disorders of mitochondrial intermediary …
[HTML][HTML] MicroRNAs and spermatogenesis
N Kotaja - Fertility and sterility, 2014 - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
Implications of testicular ACE2 and the renin–angiotensin system for SARS-CoV-2 on testis function
RC Edenfield, CA Easley IV - Nature Reviews Urology, 2022 - nature.com
Although many studies have focused on SARS-CoV-2 infection in the lungs, comparatively
little is known about the potential effects of the virus on male fertility. SARS-CoV-2 infection …
little is known about the potential effects of the virus on male fertility. SARS-CoV-2 infection …
Hormonal control of Sertoli cell metabolism regulates spermatogenesis
Hormonal regulation is essential to spermatogenesis. Sertoli cells (SCs) have functions that
reach far beyond the physical support of germ cells, as they are responsible for creating the …
reach far beyond the physical support of germ cells, as they are responsible for creating the …