Reactive oxygen species (ROS) have long been studied in the context of their direct toxic
effects on cells. As a result, ROS have conventionally been thought of as a necessary …

Intracellular bacterial pathogens cause a wide range of diseases and significantly contribute
to the morbidity and mortality associated with infectious diseases worldwide (1‐16)(Table 1) …

Francisella tularensis is a zoonotic intracellular pathogen and the causative agent of the
debilitating febrile illness tularemia. Although natural infections by F. tularensis are sporadic …

Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

Francisella tularensis is a highly virulent gram-negative intracellular bacterium that causes
the zoonotic disease tularemia. Essential for its virulence is the ability to multiply within host …

Type VI secretion systems (T6SS) are macromolecular, transenvelope machines encoded
within the genomes of most Gram-negative bacteria, including plant, animal, and human …

Mobile group II introns are bacterial retrotransposons that combine the activities of an
autocatalytic intron RNA (a ribozyme) and an intron-encoded reverse transcriptase to insert …

Invasive bronchopulmonary aspergillosis (IBPA) is a life-threatening disease in
immunocompromised patients. Although Aspergillus terreus is frequently found in the …

Ft is a facultative intracellular pathogen that infects many cell types, including neutrophils. In
previous work, we demonstrated that the type B Ft strain LVS disrupts NADPH oxidase …

The tularemia-causing bacterium Francisella tularensis is a facultative intracellular organism
with a complex intracellular lifecycle that ensures its survival and proliferation in a variety of …