Application of proteomics in cancer: recent trends and approaches for biomarkers discovery
YW Kwon, HS Jo, S Bae, Y Seo, P Song, M Song… - Frontiers in …, 2021 - frontiersin.org
Proteomics has become an important field in molecular sciences, as it provides valuable
information on the identity, expression levels, and modification of proteins. For example …
information on the identity, expression levels, and modification of proteins. For example …
The role of extracellular vesicles in the hallmarks of cancer and drug resistance
Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …
[HTML][HTML] Extracellular heat shock proteins and cancer: New perspectives
Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …
Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis
Exosomes are nano-sized extracellular vesicles released by many cells that contain
molecules characteristic of their cell of origin, including microRNA. Exosomes released by …
molecules characteristic of their cell of origin, including microRNA. Exosomes released by …
Role of exosomes in malignant glioma: microRNAs and proteins in pathogenesis and diagnosis
AB Ghaemmaghami, M Mahjoubin-Tehran… - Cell Communication and …, 2020 - Springer
Malignant gliomas are the most common and deadly type of central nervous system tumors.
Despite some advances in treatment, the mean survival time remains only about 1.25 years …
Despite some advances in treatment, the mean survival time remains only about 1.25 years …
CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/β-catenin signalling pathway
Y Li, C Liu, X Zhang, X Huang, S Liang, F Xing… - British Journal of …, 2022 - nature.com
Background Lymph node (LN) metastasis confers gastric cancer (GC) progression, poor
survival and cancer-related death. Aberrant activation of Wnt/β-catenin promotes epithelial …
survival and cancer-related death. Aberrant activation of Wnt/β-catenin promotes epithelial …
Latest advances in extracellular vesicles: from bench to bedside
T Yamamoto, N Kosaka, T Ochiya - Science and Technology of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs) are small membraned vesicles and approximately 50–150 nm in
diameter. Almost all of the type of cells releases the EVs and circulates in the body fluids …
diameter. Almost all of the type of cells releases the EVs and circulates in the body fluids …
Glioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a 'liquid gold'biopsy
Background Biomarkers that reflect glioblastoma tumour activity and treatment response are
urgently needed to help guide clinical management, particularly for recurrent disease. As the …
urgently needed to help guide clinical management, particularly for recurrent disease. As the …
The TRiCky business of protein folding in health and disease
H Ghozlan, A Cox, D Nierenberg, S King… - Frontiers in Cell and …, 2022 - frontiersin.org
Maintenance of the cellular proteome or proteostasis is an essential process that when
deregulated leads to diseases like neurological disorders and cancer. Central to …
deregulated leads to diseases like neurological disorders and cancer. Central to …
Extracellular vesicles and their role in glioblastoma
CA Whitehead, AH Kaye, KJ Drummond… - Critical Reviews in …, 2020 - Taylor & Francis
Research on the role of extracellular vesicles (EVs) in disease pathogenesis has been
rapidly growing over the last two decades. As EVs can mediate intercellular communication …
rapidly growing over the last two decades. As EVs can mediate intercellular communication …