Pioneer transcription factors initiating gene network changes
KS Zaret - Annual review of genetics, 2020 - annualreviews.org
Pioneer transcription factors have the intrinsic biochemical ability to scan partial DNA
sequence motifs that are exposed on the surface of a nucleosome and thus access silent …
sequence motifs that are exposed on the surface of a nucleosome and thus access silent …
Generating specificity in genome regulation through transcription factor sensitivity to chromatin
Cell type-specific gene expression relies on transcription factors (TFs) binding DNA
sequence motifs embedded in chromatin. Understanding how motifs are accessed in …
sequence motifs embedded in chromatin. Understanding how motifs are accessed in …
Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming
Pioneer transcription factors (TFs) access silent chromatin and initiate cell-fate changes,
using diverse types of DNA binding domains (DBDs). FoxA, the paradigm pioneer TF, has a …
using diverse types of DNA binding domains (DBDs). FoxA, the paradigm pioneer TF, has a …
Pioneer transcription factors: establishing competence for gene expression
KS Zaret, JS Carroll - Genes & development, 2011 - genesdev.cshlp.org
Transcription factors are adaptor molecules that detect regulatory sequences in the DNA
and target the assembly of protein complexes that control gene expression. Yet much of the …
and target the assembly of protein complexes that control gene expression. Yet much of the …
Structural features of transcription factors associating with nucleosome binding
Fate-changing transcription factors (TFs) scan chromatin to initiate new genetic programs
during cell differentiation and reprogramming. Yet the protein structure domains that allow …
during cell differentiation and reprogramming. Yet the protein structure domains that allow …
A positive role for histone acetylation in transcription factor access to nucleosomal DNA
Acetylation of the N-terminal tails of the core histones directly facilitates the recognition by
TFlllA of the 5s RNA gene wlthin model chromatin templates. This effect is independent of a …
TFlllA of the 5s RNA gene wlthin model chromatin templates. This effect is independent of a …
Gene regulation by steroid hormones
M Beato - Cell, 1989 - Elsevier
Gene regulation by steroid hormones has been a traditional field of research for biochemical
endocrinology since the discovery of puff induction by ecdysone in giant chromosomes of …
endocrinology since the discovery of puff induction by ecdysone in giant chromosomes of …
Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation
RR Catarino, A Stark - Genes & development, 2018 - genesdev.cshlp.org
Enhancers are important genomic regulatory elements directing cell type-specific
transcription. They assume a key role during development and disease, and their …
transcription. They assume a key role during development and disease, and their …
[引用][C] Chromatin: Structure and Function
AP Wolffe - 1998 - books.google.com
The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the
remarkable progress in chromatin research over the past three years. It has been …
remarkable progress in chromatin research over the past three years. It has been …
[HTML][HTML] Binding of the winged‐helix transcription factor HNF3 to a linker histone site on the nucleosome
LA Cirillo, CE McPherson, P Bossard, K Stevens… - The EMBO …, 1998 - embopress.org
The transcription factor HNF3 and linker histones H1 and H5 possess winged‐helix DNA‐
binding domains, yet HNF3 and other fork head‐related proteins activate genes during …
binding domains, yet HNF3 and other fork head‐related proteins activate genes during …