A systems biology investigation of curcumin potency against TGF-β-induced EMT signaling in lung cancer

S Kandagalla, BS Sharath, A Sherapura, M Grishina… - 3 Biotech, 2022 - Springer
Curcumin (diferuloylmethane) is bioactive phenolic compound which exerts diverse
antimetastatic effect. Several studies have reported the antimetastatic effect of curcumin by …

Genome-scale protein interaction network construction and topology analysis of functional hypothetical proteins in Helicobacter pylori divulges novel therapeutic …

P Gollapalli, H Manjunatha, P Shetty - Microbial Pathogenesis, 2021 - Elsevier
The emergence and spread of multi-drug resistance among Helicobacter pylori (H. pylori)
strain raise more stakes for genetic research for discovering new drugs. The quantity of …

Computational insights into the binding mode of curcumin analogues against EP300 HAT domain as potent acetyltransferase inhibitors

S Kandagalla, SB Shekarappa, H Rimac… - Journal of Molecular …, 2020 - Elsevier
Acetylation plays a key role in maintaining and balancing cellular regulation and
homeostasis. Acetyltransferases are an important class of enzymes which mediate this …