Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

1.2. Definitions Ulcerative colitis [UC] is a chronic inflammatory condition that causes
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …

The emergence of the adaptive immune system in vertebrates set the stage for evolution of
an advanced symbiotic relationship with the intestinal microbiota. The defining features of …

Ulcerative colitis is a lifelong disease arising from an interaction between genetic and
environmental factors, observed predominantly in the developed countries of the world. The …

Strategies for management of inflammatory bowel diseases are shifting from simple control
of symptoms toward full control of these diseases (clinical and endoscopic remission), with …

Guidelines for clinical practice are aimed to indicate preferred approaches to medical
problems as established by scientifically valid research. Double-blind placebo controlled …

In recent years, investigators have readdressed the complex issues involved in the
classification of inflammatory bowel diseases. In 2003, a Working Party of investigators with …

The predominantly anaerobic microbiota of the distal ileum and colon contain an
extraordinarily complex variety of metabolically active bacteria and fungi that intimately …

Crohn's disease and ulcerative colitis are idiopathic, chronic, relapsing, inflammatory
conditions that are immunologically mediated. Although their exact etiologies remain …

Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …