Blood levels of the amino acid phenylalanine, as well as of the tryptophan breakdown
product kynurenine, are found to be elevated in human immunodeficiency virus type 1 (HIV …

People with HIV are at increased risk for depression, though the neurobiological
mechanisms underlying this are unclear. In the last decade, there has been a substantial …

Background. We explored the establishment of abnormal blood-brain barrier (BBB)
permeability and its relationship to neuropathogenesis during primary human …

This observational study of 123 Thai participants sought to determine the rate and severity of
affective symptoms during acute HIV infection (AHI) and possible associations to disease …

Objective: To examine whether persons with asymptomatic neurocognitive impairment (ANI)
were more likely to show progression to mild neurocognitive disorder or HIV-associated …

This observational cross-sectional study of 152 people with HIV (PWH) examined the effects
of age and estimated duration of HIV infection (EDI) on depressive and anxiety symptoms …

Aims This study examined the changes and the predictors of suicide ideation/suicide attempt
and the moderating effects of psychosocial factors on the suicide ideation/suicide attempts …

Background: Depression is a frequent comorbidity in HIV infection that has been associated
with worse treatment outcomes and increased mortality. Recent studies suggest that …

Integrase strand transfer inhibitors (INSTI) are a main component of the current antiretroviral
regimens recommended for treatment of HIV infection. However, little is known about the …

Objective: Mood disorders and neurocognitive impairments are debilitating conditions
among patients with HIV/AIDS. How these comorbidities interact and their relationships to …