Autoimmune hepatitis (AIH) is a severe liver disease that affects children and adults
worldwide. The diagnosis of AIH relies on increased serum transaminase and …

Clinical practice guidelines are defined as ''systematically developed statements to assist
practitioner and patient decisions about appropriate heath care for specific clinical …

Abstract Programmed death 1 (PD-1) and its ligands, namely PD-L1 and PD-L2, are one of
the key factors responsible for inhibitory T cell signaling, mediating the mechanisms of …

Background & Aims Population-based studies of the clinical course of autoimmune hepatitis
are scarce. We conducted a nationwide study of incidence, prevalence, prognosis, and …

As a chronic inflammatory disease of the liver, the pa-thogenic mechanisms of autoimmune
hepatitis (AIH) have not yet been elucidated, with prognosis and diagnosis remaining …

Hepatic inflammation is a common finding during a variety of liver diseases including drug-
induced liver toxicity. The inflammatory phenotype can be attributed to the innate immune …

Liver damage leads to an inflammatory response and to the activation and proliferation of
mesenchymal cell populations within the liver which remodel the extracellular matrix as part …

Background & Aims The risk of hepatocellular carcinoma (HCC) in patients with autoimmune
hepatitis (AIH) is unclear. We conducted a systematic review and meta-analysis of the …

Autoimmune hepatitis (AIH), a liver disorder affecting both children and adults, is
characterized by inflammatory liver histology, elevated transaminase levels, circulating …

Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary
cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate …