Background We conducted a systematic review of incidence rates in England over a sixty-
year period to determine the extent to which rates varied along accepted (age, sex) and less …

Early intervention for potentially serious disorder is a fundamental feature of healthcare
across the spectrum of physical illness. It has been a major factor in the reductions in …

Introduction: Prevention of psychosis has become a major objective of modern clinical
psychiatry. An increasing number of new services have been established in Europe and in …

Background Psychosis is a serious mental condition characterised by a loss of contact with
reality. There may be a prodromal period or stage of psychosis, where early signs of …

The first rate-limiting step to successfully translate prevention of psychosis in to clinical
practice is to establish specialised Clinical High Risk for Psychosis (CHR-P) services. This …

There continues to be controversy concerning the long term benefits of specialized early
intervention programs (SEI) for psychotic disorders. Recent reports of five year outcomes for …

Aim In a survey conducted in the L ausanne catchment area in 2000, we could estimate on
the basis of file assessment that first‐episode psychosis (FEP) patients had psychotic …

Abstract Clinical High Risk for Psychosis (CHR-P) services have been primarily developed
to support young people with attenuated symptoms (indicated prevention). No evidence …

BackgroundDespite the increasing development of early intervention services for psychosis,
little is known about their cost-effectiveness. We assessed the cost-effectiveness of Outreach …

Background Little is known about patients with a first episode of psychosis (FEP) who had
first presented to prodromal services with an “at risk mental state”(ARMS) before making the …