Colorectal liver metastasis: molecular mechanism and interventional therapy
H Zhou, Z Liu, Y Wang, X Wen, EH Amador… - Signal transduction and …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …
Characterisation and classification of oligometastatic disease: a European Society for Radiotherapy and Oncology and European Organisation for Research and …
M Guckenberger, Y Lievens, AB Bouma… - The Lancet …, 2020 - thelancet.com
Oligometastatic disease has been proposed as an intermediate state between localised and
systemically metastasised disease. In the absence of randomised phase 3 trials, early …
systemically metastasised disease. In the absence of randomised phase 3 trials, early …
Outcomes of observation vs stereotactic ablative radiation for oligometastatic prostate cancer: the ORIOLE phase 2 randomized clinical trial
Importance Complete metastatic ablation of oligometastatic prostate cancer may provide an
alternative to early initiation of androgen deprivation therapy (ADT). Objective To determine …
alternative to early initiation of androgen deprivation therapy (ADT). Objective To determine …
[HTML][HTML] Defining oligometastatic disease from a radiation oncology perspective: An ESTRO-ASTRO consensus document
Y Lievens, M Guckenberger, D Gomez, M Hoyer… - Radiotherapy and …, 2020 - Elsevier
Background Recognizing the rapidly increasing interest and evidence in using metastasis-
directed radiotherapy (MDRT) for oligometastatic disease (OMD), ESTRO and ASTRO …
directed radiotherapy (MDRT) for oligometastatic disease (OMD), ESTRO and ASTRO …
Contemporary radiotherapy: present and future
Oncology care is increasingly a multidisciplinary endeavour, and radiation therapy
continues to have a key role across the disease spectrum in nearly every cancer. However …
continues to have a key role across the disease spectrum in nearly every cancer. However …
Long-term outcomes and genetic predictors of response to metastasis-directed therapy versus observation in oligometastatic prostate cancer: analysis of STOMP and …
Clinical trials frequently include multiple end points that mature at different times. The initial
report, typically based on the primary end point, may be published when key planned co …
report, typically based on the primary end point, may be published when key planned co …
Modern therapeutic approaches for the treatment of malignant liver tumours
H Petrowsky, R Fritsch, M Guckenberger… - Nature reviews …, 2020 - nature.com
Malignant liver tumours include a wide range of primary and secondary tumours. Although
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …
Safety and survival rates associated with ablative stereotactic radiotherapy for patients with oligometastatic cancer: a systematic review and meta-analysis
Importance The oligometastatic paradigm postulates that patients with a limited number of
metastases can be treated with ablative local therapy to each site of disease with curative …
metastases can be treated with ablative local therapy to each site of disease with curative …
Molecular characterization of colorectal cancer related peritoneal metastatic disease
KJ Lenos, S Bach, L Ferreira Moreno… - Nature …, 2022 - nature.com
A significant proportion of colorectal cancer (CRC) patients develop peritoneal metastases
(PM) in the course of their disease. PMs are associated with a poor quality of life, significant …
(PM) in the course of their disease. PMs are associated with a poor quality of life, significant …
The oligometastatic spectrum in the era of improved detection and modern systemic therapy
Metastases remain the leading cause of cancer-related mortality. The oligometastasis
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …