Non-integrating lentiviral vectors in clinical applications: A glance through

N Gurumoorthy, F Nordin, GJ Tye… - Biomedicines, 2022 - mdpi.com
Lentiviral vectors (LVs) play an important role in gene therapy and have proven successful
in clinical trials. LVs are capable of integrating specific genetic materials into the target cells …

Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons

LC Steg, GL Shireby, J Imm, JP Davies, A Franklin… - Molecular brain, 2021 - Springer
Induced pluripotent stem cells (iPSCs) and their differentiated neurons (iPSC-neurons) are a
widely used cellular model in the research of the central nervous system. However, it is …

Comparison of the calcium signaling alterations in GABA-ergic medium spiny neurons produced from iPSCs of different origins

AA Oshkolova, DA Grekhnev, AA Kruchinina… - Biochimie, 2024 - Elsevier
Disease models based on induced pluripotent stem cells (iPSCs) are in high demand
because of their physiological adequacy and well-reproducibility of the pathological …

Novel epigenetic clock for fetal brain development predicts fetal epigenetic age for iPSCs and iPSC-derived neurons.

LC Steg, GL Shireby, J Imm, JP Davies, R Flynn… - 2020 - researchsquare.com
Induced pluripotent stem cells (iPSCs) and their differentiated neurons (iPSC-neurons) are a
widely used cellular model in the research of the central nervous system. However, it is …