Present and future of bronchopulmonary dysplasia

L Bonadies, P Zaramella, A Porzionato… - Journal of clinical …, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants
born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal …

[HTML][HTML] Emerging role of metabolic reprogramming in hyperoxia-associated neonatal diseases

T Sun, H Yu, D Li, H Zhang, J Fu - Redox Biology, 2023 - Elsevier
Oxygen therapy is common during the neonatal period to improve survival, but it can
increase the risk of oxygen toxicity. Hyperoxia can damage multiple organs and systems in …

Bronchopulmonary dysplasia and perinatal characteristics predict 1-year respiratory outcomes in newborns born at extremely low gestational age: a prospective …

RL Keller, R Feng, SB DeMauro, T Ferkol… - The Journal of …, 2017 - Elsevier
Objective To assess the utility of clinical predictors of persistent respiratory morbidity in
extremely low gestational age newborns (ELGANs). Study design We enrolled ELGANs (< …

Phenotypes of bronchopulmonary dysplasia

SH Wang, PN Tsao - International Journal of Molecular Sciences, 2020 - mdpi.com
Bronchopulmonary dysplasia (BPD) is the most common chronic morbidity in preterm
infants. In the absence of effective interventions, BPD is currently a major therapeutic …

Omics approaches: interactions at the maternal–fetal interface and origins of child health and disease

M Ozen, N Aghaeepour, I Marić, RJ Wong… - Pediatric …, 2023 - nature.com
Immunoperinatology is an emerging field. Transdisciplinary efforts by physicians, physician‐
scientists, basic science researchers, and computational biologists have made substantial …

Metabolic reprogramming in the pathogenesis of chronic lung diseases, including BPD, COPD, and pulmonary fibrosis

H Zhao, PA Dennery, H Yao - American Journal of …, 2018 - journals.physiology.org
The metabolism of nutrient substrates, including glucose, glutamine, and fatty acids,
provides acetyl-CoA for the tricarboxylic acid cycle to generate energy, as well as …

Pathogenesis of bronchopulmonary dysplasia: role of oxidative stress from 'Omics' studies

A Kimble, ME Robbins, M Perez - Antioxidants, 2022 - mdpi.com
Bronchopulmonary dysplasia (BPD) remains the most common respiratory complication of
prematurity as younger and smaller infants are surviving beyond the immediate neonatal …

Biomarkers for bronchopulmonary dysplasia in the preterm infant

L Rivera, R Siddaiah, C Oji-Mmuo, GR Silveyra… - Frontiers in …, 2016 - frontiersin.org
Bronchopulmonary dysplasia (BPD) is a chronic inflammatory lung disease of very-low-birth-
weight (VLBW) preterm infants, associated with arrested lung development and a need for …

Early airway microbial metagenomic and metabolomic signatures are associated with development of severe bronchopulmonary dysplasia

CV Lal, J Kandasamy, K Dolma… - … of Physiology-Lung …, 2018 - journals.physiology.org
The pathogenesis of bronchopulmonary dysplasia (BPD) is not well understood. We
previously identified differences in the airway microbiome at birth between preterm infants …

Preventing bronchopulmonary dysplasia: new tools for an old challenge

M Álvarez-Fuente, L Moreno, JA Mitchell, IK Reiss… - Pediatric …, 2019 - nature.com
Bronchopulmonary dysplasia (BPD) is the most prevalent chronic lung disease in infants
and presents as a consequence of preterm birth. Due to the lack of effective preventive and …