[HTML][HTML] Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders

Y Chen, J Xu, Y Chen - Nutrients, 2021 - mdpi.com
Emerging evidence indicates that gut microbiota is important in the regulation of brain
activity and cognitive functions. Microbes mediate communication among the metabolic …

[HTML][HTML] Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia

E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility

NJ Spencer, H Hu - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

[HTML][HTML] Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

[HTML][HTML] Epigenetics in depression and gut-brain axis: A molecular crosstalk

N Begum, A Mandhare, KP Tryphena… - Frontiers in Aging …, 2022 - frontiersin.org
Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …

[HTML][HTML] Understanding the gut–brain axis and its therapeutic implications for neurodegenerative disorders

Y Zheng, L Bonfili, T Wei, AM Eleuteri - Nutrients, 2023 - mdpi.com
The gut–brain axis (GBA) is a complex bidirectional communication network connecting the
gut and brain. It involves neural, immune, and endocrine communication pathways between …

[HTML][HTML] Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine

Z Li, MM Hao, C Van den Haute, V Baekelandt… - Elife, 2019 - elifesciences.org
The enteric nervous system controls a variety of gastrointestinal functions including intestinal
motility. The minimal neuronal circuit necessary to direct peristalsis is well-characterized but …

Unveiling the role of gut-brain axis in regulating neurodegenerative diseases: A comprehensive review

H Yadav, R Bhardwaj, A Bakshi, S Gupta, SK Maurya - Life Sciences, 2023 - Elsevier
Emerging evidence have shown the importance of gut microbiota in regulating brain
functions. The diverse molecular mechanisms involved in cross-talk between gut and brain …

Implications of microbe-derived ɣ-aminobutyric acid (GABA) in gut and brain barrier integrity and GABAergic signaling in Alzheimer's disease

KA Conn, EM Borsom, EK Cope - Gut microbes, 2024 - Taylor & Francis
The gut microbial ecosystem communicates bidirectionally with the brain in what is known
as the gut-microbiome-brain axis. Bidirectional signaling occurs through several pathways …

Neonatal antibiotics have long term sex‐dependent effects on the enteric nervous system

SSB Poon, LY Hung, Q Wu, P Parathan… - The Journal of …, 2022 - Wiley Online Library
Infants and young children receive the highest exposures to antibiotics globally. Although
there is building evidence that early life exposure to antibiotics increases susceptibility to …