The cyanine platforms including cyanine, hemicyanine, and squaraine are good candidates
for developing chemosensors because of their excellent photophysical properties …

As one of the most representative hypoxic enzymes, nitroreductases (NTRs) play
momentous roles in malignant tumor progression, metastasis, invasion and angiogenesis …

To maximize tumor excision and minimize collateral damage are the primary goals of cancer
surgery. Emerging molecular imaging techniques have made “image-guided surgery” …

Large tumours contain regions with very low intracellular O2 concentrations. Known as
hypoxia, this feature of tumours yields a highly reducing environment owing to the presence …

Near-infrared (NIR) fluorescence imaging is a noninvasive technique that provides
numerous advantages for the real-time in vivo monitoring of biological information in living …

Personalized oncology significantly relies on the development of cancer theranostic agents
to integrate cancer therapeutics and diagnostics. Current most common strategy for …

A novel “turn-on” fluorescent probe HP for hypoxia imaging was designed and synthesized
based on rhodamine B and a naphthalimide fluorophore. The fluorescence of HP is very …

Continued advancement in bioresponsive fluorescence imaging requires new classes of
activatable fluorescent probes that emit near-infrared fluorescence with wavelengths above …

The ultimate goal of cancer surgery is to maximize the excision of tumorous tissue with
minimal damage to the collateral normal tissues, reduce the postoperative recurrence, and …

New sulforhodamine-based fluorescent'turn-on'probes have been developed for the direct
imaging of cellular hypoxia. Rapid access to this novel class of water-soluble'azobenzene …