Major depressive disorder is a leading cause of disability worldwide. Because conventional
therapies are ineffective in many patients, novel strategies are needed to overcome …

Depression has been associated with inflammatory pathophysiological mechanisms,
including alterations in amount of circulating immune cells. However, no meta-analysis …

Importance The totality of the societal and individual impact of treatment-resistant
depression (TRD) is unknown, as is the potential to prognosticate TRD. The generalizability …

Patients with treatment-resistant depression (TRD) have higher rates of relapse and
pronounced decreases in daily functioning and health-related quality of life compared to …

Nowadays depression is considered as a systemic illness with different biological
mechanisms involved in its etiology, including inflammatory response, hypothalamic …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

There is considerable diversity in how treatment-resistant depression (TRD) is defined.
However, every definition incorporates the concept that patients with TRD have not …

Objective To present the first real-world data of patients with treatment-resistant depression
(TRD) treated with esketamine through a French cohort Temporary Authorisation for Use …

Background Treatment-resistant depression (TRD) may represent a substantial proportion of
major depressive disorder (MDD); however, the risk of mortality in TRD is still incompletely …

Background To determine the incidence of Treatment-Resistant Depression (TRD) in Spain
and to estimate its economic burden, using real world data. Methods A retrospective …