Novel drug developmental strategies for treatment‐resistant depression
Major depressive disorder is a leading cause of disability worldwide. Because conventional
therapies are ineffective in many patients, novel strategies are needed to overcome …
therapies are ineffective in many patients, novel strategies are needed to overcome …
Immune cell composition in unipolar depression: a comprehensive systematic review and meta-analysis
NV Sørensen, BH Frandsen, S Orlovska-Waast… - Molecular …, 2023 - nature.com
Depression has been associated with inflammatory pathophysiological mechanisms,
including alterations in amount of circulating immune cells. However, no meta-analysis …
including alterations in amount of circulating immune cells. However, no meta-analysis …
Association of treatment-resistant depression with patient outcomes and health care resource utilization in a population-wide study
J Lundberg, T Cars, SÅ Lööv, J Söderling… - JAMA …, 2023 - jamanetwork.com
Importance The totality of the societal and individual impact of treatment-resistant
depression (TRD) is unknown, as is the potential to prognosticate TRD. The generalizability …
depression (TRD) is unknown, as is the potential to prognosticate TRD. The generalizability …
Long-term safety and maintenance of response with esketamine nasal spray in participants with treatment-resistant depression: interim results of the SUSTAIN-3 study
N Zaki, L Chen, R Lane, T Doherty… - …, 2023 - nature.com
Patients with treatment-resistant depression (TRD) have higher rates of relapse and
pronounced decreases in daily functioning and health-related quality of life compared to …
pronounced decreases in daily functioning and health-related quality of life compared to …
Depression: Biological markers and treatment
Nowadays depression is considered as a systemic illness with different biological
mechanisms involved in its etiology, including inflammatory response, hypothalamic …
mechanisms involved in its etiology, including inflammatory response, hypothalamic …
[HTML][HTML] Lower urinary tract symptoms in depression: a review
DJ Anderson, A Aucoin, CR Toups… - Health psychology …, 2023 - ncbi.nlm.nih.gov
Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …
population as patients age with approximately a third of individuals experiencing LUTS …
[HTML][HTML] The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF)
HA Sackeim, ST Aaronson, MT Bunker… - Journal of psychiatric …, 2019 - Elsevier
There is considerable diversity in how treatment-resistant depression (TRD) is defined.
However, every definition incorporates the concept that patients with TRD have not …
However, every definition incorporates the concept that patients with TRD have not …
Esketamine nasal spray in patients with treatment-resistant depression: the real-world experience in the French cohort early-access programme
L Samalin, M Rothärmel, L Mekaoui… - … Journal of Psychiatry …, 2022 - Taylor & Francis
Objective To present the first real-world data of patients with treatment-resistant depression
(TRD) treated with esketamine through a French cohort Temporary Authorisation for Use …
(TRD) treated with esketamine through a French cohort Temporary Authorisation for Use …
All-cause mortality in patients with treatment-resistant depression: a cohort study in the US population
G Li, D Fife, G Wang, JJ Sheehan, R Bodén… - Annals of General …, 2019 - Springer
Background Treatment-resistant depression (TRD) may represent a substantial proportion of
major depressive disorder (MDD); however, the risk of mortality in TRD is still incompletely …
major depressive disorder (MDD); however, the risk of mortality in TRD is still incompletely …
[HTML][HTML] Economic impact of treatment-resistant depression: a retrospective observational study
V Pérez-Sola, M Roca, J Alonso, A Gabilondo… - Journal of Affective …, 2021 - Elsevier
Background To determine the incidence of Treatment-Resistant Depression (TRD) in Spain
and to estimate its economic burden, using real world data. Methods A retrospective …
and to estimate its economic burden, using real world data. Methods A retrospective …