Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism
HK Park, RS Ahima - Metabolism, 2015 - Elsevier
Leptin is secreted by adipose tissue and regulates energy homeostasis, neuroendocrine
function, metabolism, immune function and other systems through its effects on the central …
function, metabolism, immune function and other systems through its effects on the central …
Obesity and thyroid axis
K Walczak, L Sieminska - … journal of environmental research and public …, 2021 - mdpi.com
Development of obesity is primarily the result of imbalance between energy intake and
energy expenditure. Thyroid hormones influence energy expenditure by regulating cellular …
energy expenditure. Thyroid hormones influence energy expenditure by regulating cellular …
Leptin in human physiology and pathophysiology
CS Mantzoros, F Magkos… - American Journal …, 2011 - journals.physiology.org
Leptin, discovered through positional cloning 15 years ago, is an adipocyte-secreted
hormone with pleiotropic effects in the physiology and pathophysiology of energy …
hormone with pleiotropic effects in the physiology and pathophysiology of energy …
Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases
The goal of this review is to place the exciting advances that have occurred in our
understanding of the molecular biology of the types 1, 2, and 3 (D1, D2, and D3 …
understanding of the molecular biology of the types 1, 2, and 3 (D1, D2, and D3 …
Towards a molecular understanding of adaptive thermogenesis
BB Lowell, BM Spiegelman - Nature, 2000 - nature.com
Obesity results when energy intake exceeds energy expenditure. Naturally occurring genetic
mutations, as well as ablative lesions, have shown that the brain regulates both aspects of …
mutations, as well as ablative lesions, have shown that the brain regulates both aspects of …
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling
B Gereben, AM Zavacki, S Ribich, BW Kim… - Endocrine …, 2008 - academic.oup.com
The iodothyronine deiodinases initiate or terminate thyroid hormone action and therefore
are critical for the biological effects mediated by thyroid hormone. Over the years, research …
are critical for the biological effects mediated by thyroid hormone. Over the years, research …
Hypothalamus‐pituitary‐thyroid axis
TM Ortiga‐Carvalho, MI Chiamolera… - Comprehensive …, 2011 - Wiley Online Library
The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …
The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity
BE Wisse - Journal of the American society of nephrology, 2004 - journals.lww.com
The metabolic effects of obesity have made this highly prevalent disease one of the most
common risk factors for diabetes, hypertension, and atherosclerosis, the leading causes of …
common risk factors for diabetes, hypertension, and atherosclerosis, the leading causes of …
Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human
A Giustina, JD Veldhuis - Endocrine reviews, 1998 - academic.oup.com
A. Genetic, molecular, and transgenic models B. Human GH rhythms III. Neuropeptide
Regulation of the GH Axis: Somatostatin and GHRH
Regulation of the GH Axis: Somatostatin and GHRH