Complications of Cushing's syndrome: state of the art

R Pivonello, AM Isidori, MC De Martino… - The lancet Diabetes & …, 2016 - thelancet.com
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and
excessive secretion of cortisol. The syndrome is associated with increased mortality and …

The treatment of Cushing's disease

R Pivonello, M De Leo, A Cozzolino… - Endocrine …, 2015 - academic.oup.com
Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Treatment of Cushing's syndrome: an endocrine society clinical practice guideline

LK Nieman, BMK Biller, JW Findling… - The Journal of …, 2015 - academic.oup.com
Objective: The objective is to formulate clinical practice guidelines for treating Cushing's
syndrome. Participants: Participants include an Endocrine Society-appointed Task Force of …

Cushing's syndrome

A Lacroix, RA Feelders, CA Stratakis, LK Nieman - The lancet, 2015 - thelancet.com
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's
syndrome, including debilitating morbidities and increased mortality. Genetic and molecular …

Cushing's syndrome: epidemiology and developments in disease management

ST Sharma, LK Nieman, RA Feelders - Clinical epidemiology, 2015 - Taylor & Francis
Cushing's syndrome is a rare disorder resulting from prolonged exposure to excess
glucocorticoids. Early diagnosis and treatment of Cushing's syndrome is associated with a …

Metabolic comorbidities in Cushing's syndrome

F Ferrau, M Korbonits - European Journal of Endocrinology, 2015 - academic.oup.com
Cushing's syndrome (CS) patients have increased mortality primarily due to cardiovascular
events induced by glucocorticoid (GC) excess-related severe metabolic changes. Glucose …

Advances in the medical treatment of Cushing's syndrome

RA Feelders, J Newell-Price, R Pivonello… - The lancet Diabetes & …, 2019 - thelancet.com
Cushing's syndrome is associated with multisystem morbidity and, when suboptimally
treated, increased mortality. Medical therapy is an option for patients if surgery is not …

Outcome of bilateral adrenalectomy in Cushing's syndrome: a systematic review

K Ritzel, F Beuschlein, A Mickisch… - The Journal of …, 2013 - academic.oup.com
Background: The outcome of bilateral adrenalectomy (BADx) in patients with Cushing's
syndrome (CS) is not well characterized. Methods: A literature search was performed with …

Transcriptional bursting and co-bursting regulation by steroid hormone release pattern and transcription factor mobility

DA Stavreva, DA Garcia, G Fettweis, PR Gudla, GF Zaki… - Molecular cell, 2019 - cell.com
Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but the
mechanisms regulating this process are unclear. Although many physiological signals …

Recurrence after pituitary surgery in adult Cushing's disease: a systematic review on diagnosis and treatment

LT Braun, G Rubinstein, S Zopp, F Vogel… - Endocrine, 2020 - Springer
Purpose Recurrence after pituitary surgery in Cushing's disease (CD) is a common problem
ranging from 5%(minimum) to 50%(maximum) after initially successful surgery, respectively …