Common variable immunodeficiency (CVID) is a heterogeneous group of inborn errors of
immunity characterized by reduced serum concentrations of different immunoglobulin …

Objectives: The aim of this study was to evaluate the frequency of autoimmunity in primary
antibody deficiency (PAD). Methods: A total of 471 patients with PADs enrolled in this …

Vaccination is the most effective measure to prevent infections in the general population. Its
efficiency strongly depends on the function and composition of the immune system. If the …

Background Common variable immunodeficiency (CVID) is one of the most prevalent
symptomatic primary immunodeficiencies (PIDs), which manifests a wide clinical variability …

Common variable immunodeficiency (CVID) is the most prevalent symptomatic type of
human primary immunodeficiency diseases (PID). Clinically, CVID is characterized by …

In this study, a compressional-puffing process (CPP) was used to pretreat Sargassum
hemiphyllum (SH) and then fucoidan was extracted from SH by hot water. Three fucoidan …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the
development of autoantibodies that drive disease pathogenesis. Genetic studies have …

Systemic sclerosis (SSc) is a rare disease with a prevalence ranging from 7 to 700 cases per
million. Like with most autoimmune diseases, both environmental and genetic factors are …

The altered wiring of signaling pathways downstream of antigen receptors of T and B cells
contributes to the dysregulation of the adaptive immune system, potentially causing …

Background: Primary antibody deficiency (PAD) comprises a range of diseases from early to
late terminal B cells defects and is associated with the various clinical complications …