Pulmonary cryptococcosis describes an invasive lung mycosis caused by Cryptococcus
neoformans or Cryptococcus gattii complex. It is often a high-consequence disease in both …

Central nervous system (CNS) cryptococcosis in non-HIV infected patients affects solid
organ transplant (SOT) recipients, patients with malignancy, rheumatic disorders, other …

SARS-CoV-2 may activate both innate and adaptive immune responses ultimately leading to
a dysregulated immune response prompting the use of immunomodulatory therapy …

Glucocorticoids are widespread anti-inflammatory medications used in medical practice. The
immunosuppressive effects of systemic glucocorticoids and increased susceptibility to …

Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of
these infections is still limited due to the low bioavailability and toxicity, requiring therapeutic …

A total of 476 European isolates (310 Cryptococcus neoformans var. grubii, 150 C.
neoformans var. neoformans, and 16 C. gattii species complex) from both clinical and …

New fluconazole-loaded, 6-Anhydro-α-l-Galacto-β-d-Galactan hydrogels incorporated with
nanohydroxyapatite were prepared and their physicochemical features (XRD, X-ray …

Background Cryptococcal meningitis (CM) is the most common fungal infection of the central
nervous system and has high morbidity and mortality. Almost studies about prognostic …

Cryptococcal meningitis (CM) is an invasive fungal disease that currently poses a threat to
human health worldwide, with high morbidity and mortality, particularly in …

Cryptococcosis caused by Cryptococcus gattii, is a life threatening fungal infection with
recently increasing prevalence. C. gattii is a species complex comprising multiple …