Quaternary ammonium salts: insights into synthesis and new directions in antibacterial applications
Z Zhou, S Zhou, X Zhang, S Zeng, Y Xu… - Bioconjugate …, 2023 - ACS Publications
The overuse of antibiotics has led to the emergence of a large number of antibiotic-resistant
genes in bacteria, and increasing evidence indicates that a fungicide with an antibacterial …
genes in bacteria, and increasing evidence indicates that a fungicide with an antibacterial …
Current Development of Thiazole-Containing Compounds as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus
H Liu, T Xu, Z Xue, M Huang, T Wang… - ACS Infectious …, 2024 - ACS Publications
The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …
A new discovery of unique 13-(benzimidazolylmethyl) berberines as promising broad-spectrum antibacterial agents
H Sun, ZZ Li, P Jeyakkumar, ZL Zang… - Journal of Agricultural …, 2022 - ACS Publications
A new hybridization of berberine and benzimidazoles was performed to produce 13-
(benzimidazolylmethyl) berberines (BMB) as potentially broad-spectrum antibacterial agents …
(benzimidazolylmethyl) berberines (BMB) as potentially broad-spectrum antibacterial agents …
SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria
Antibiotic-resistant bacteria represent a serious threat to modern medicine and human life.
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …
Unique azolyl acylhydrazonyl hybridization of aloe emodins to access potential antibacterial agents
YX Wang, Z Deng, A Bibi, B Fang… - Chinese Journal of …, 2024 - Wiley Online Library
Comprehensive Summary A type of unique azole‐hybridized acylhydrazonyl aloe emodins
(AAEs) were developed as new antibacterial agents for combating bacterial infections …
(AAEs) were developed as new antibacterial agents for combating bacterial infections …
Exploring the dual effect of novel 1, 4-diarylpyranopyrazoles as antiviral and anti-inflammatory for the management of SARS-CoV-2 and associated inflammatory …
COVID-19 and associated substantial inflammations continue to threaten humankind
triggering death worldwide. So, the development of new effective antiviral and anti …
triggering death worldwide. So, the development of new effective antiviral and anti …
Lipophilic Ga complex with broad-spectrum antimicrobial activity and the ability to overcome gallium resistance in both Pseudomonas aeruginosa and Staphylococcus …
Antibiotic resistance (AR) necessitates the discovery of new antimicrobials with alternative
mechanisms of action to those employed by conventional antibiotics. One such strategy …
mechanisms of action to those employed by conventional antibiotics. One such strategy …
Synthesis and antibacterial medicinal evaluation of carbothioamido hydrazonyl thiazolylquinolone with multitargeting antimicrobial potential to combat increasingly …
ZL Zang, YX Wang, N Battini, WW Gao… - European Journal of …, 2024 - Elsevier
The global microbial resistance is a serious threat to human health, and multitargeting
compounds are considered to be promising to combat microbial resistance. In this work, a …
compounds are considered to be promising to combat microbial resistance. In this work, a …
Exploring the structure-activity relationships of diphenylurea as an antibacterial scaffold active against methicillin-and vancomycin-resistant Staphylococcus aureus
A set of structurally related diphenylurea derivatives bearing aminoguanidine moiety were
synthesized, and their antibacterial activity was assessed against a panel of multi-drug …
synthesized, and their antibacterial activity was assessed against a panel of multi-drug …
Antibacterial and anti-quorum sensing activities of a substituted thiazole derivative against methicillin-resistant Staphylococcus aureus and other multidrug-resistant …
Management of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) is
still challenging. We herein report the antibacterial and anti-quorum sensing (anti-QS) …
still challenging. We herein report the antibacterial and anti-quorum sensing (anti-QS) …