Euphorbia diterpenoids: isolation, structure, bioactivity, biosynthesis, and synthesis (2013–2021)

Z Zhan, S Li, W Chu, S Yin - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2013 to 2021 As the characteristic metabolites of Euphorbia plants, Euphorbia
diterpenoids have always been a hot topic in related science communities due to their …

Jatrophane and rearranged jatrophane-type diterpenes: Biogenesis, structure, isolation, biological activity and SARs (1984–2019)

M Fattahian, M Ghanadian, Z Ali, IA Khan - Phytochemistry reviews, 2020 - Springer
Diterpene compounds specially macrocyclic ones comprising jatrophane, lathyrane,
terracinolide, ingenane, pepluane, paraliane, and segetane skeletons occurring in plants of …

Diterpenes and their derivatives as potential anticancer agents

MT Islam - Phytotherapy Research, 2017 - Wiley Online Library
As therapeutic tools, diterpenes and their derivatives have gained much attention of the
medicinal scientists nowadays. It is due to their pledging and important biological activities …

Euphorbia dendroides Latex as a Source of Jatrophane Esters: Isolation, Structural Analysis, Conformational Study, and Anti-CHIKV Activity

M Esposito, LF Nothias, H Nedev… - Journal of natural …, 2016 - ACS Publications
An efficient process was used to isolate six new jatrophane esters, euphodendroidins J (3),
K (5), L (6), M,(8), N (10), and O (11), along with seven known diterpenoid esters, namely …

Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia

WP Wang, K Jiang, P Zhang, KK Shen, SJ Qu, XP Yu… - Phytochemistry, 2018 - Elsevier
A phytochemical investigation on the aerial part of Euphorbia helioscopia (Euphorbiaceae)
led to the isolation of 22 highly oxygenated diterpenoids with structural types of ent …

New Insights on Euphorbia dendroides L. (Euphorbiaceae): Polyphenol Profile and Biological Properties of Hydroalcoholic Extracts from Aerial Parts

A Smeriglio, M Denaro, D Trombetta, S Ragusa… - Plants, 2021 - mdpi.com
Euphorbia dendroides L. is a rounded shrub commonly found in the Mediterranean area
well-known, since ancient times, for its traditional use. The aim of the present study was to …

Diterpenoids of terrestrial origin

JR Hanson - Natural product reports, 2015 - pubs.rsc.org
Covering: January to December 2013. Previous review, Nat. Prod. Rep., 2013, 30, 1346–
1356 This review covers the isolation and chemistry of diterpenoids from terrestrial as …

Evaluation of Jatrophane Esters from Euphorbia spp. as Modulators of Candida albicans Multidrug Transporters

M Esposito, S Nim, LF Nothias, JF Gallard… - Journal of natural …, 2017 - ACS Publications
Twenty-nine jatrophane esters (1–10, 12–30) and one lathyrane (11) diterpenoid ester
isolated from Euphorbia species were evaluated for their capacity to inhibit drug-efflux …

Discovery of a novel highly potent and low-toxic jatrophane derivative enhancing the P-glycoprotein-mediated doxorubicin sensitivity of MCF-7/ADR cells

A Maimaitijiang, B Wang, H Yang, D Tang, Y Liu… - European Journal of …, 2022 - Elsevier
Use of novel modulators targeting P-glycoprotein (P-gp, ABCB1 transporter) is among the
most accepted strategies for overcoming multidrug resistance in cancer chemotherapy. In …

New approaches with natural product drugs for overcoming multidrug resistance in cancer

J Dinic, A Podolski-Renic, T Stankovic… - Current …, 2015 - ingentaconnect.com
Resistance to chemotherapeautic drugs is one of the main obstacles to effective cancer
treatment. Multidrug resistance (MDR) is defined as resistance to structurally and/or …