BACKGROUND Many key global sustainability challenges are closely intertwined
(examples are provided in the figure). These challenges include air pollution, biodiversity …

▪ Abstract Fluid flow at the microscale exhibits unique phenomena that can be leveraged to
fabricate devices and components capable of performing functions useful for biological …

This paper describes a procedure that makes it possible to design and fabricate (including
sealing) microfluidic systems in an elastomeric material poly (dimethylsiloxane)(PDMS) in …

The area of micro total analysis systems, also called “lab on a chip”, or miniaturized analysis
systems, is growing rapidly. Since the excellent research documented in many publications …

In this work we report on a simple inertial microfluidic device that achieves continuous multi-
particle separation using the principle of Dean-coupled inertial migration in spiral …

SUMMARY PCR has revolutionized the field of infectious disease diagnosis. To overcome
the inherent disadvantage of cost and to improve the diagnostic capacity of the test …

After having reviewed some aspects of microfluidic system preparation in the first part (1), in
this second part of the review we will cover a number of standard operations (namely …

Systems approaches to disease are grounded in the idea that disease-perturbed protein
and gene regulatory networks differ from their normal counterparts; we have been pursuing …

A rapidly emerging field in lab-on-a-chip (LOC) research is the development of devices to
improve the health of people in developing countries. In this review, we identify diseases …

The importance of accurate sample preparation techniques cannot be overstated--
meticulous sample preparation is essential. Often overlooked, it is the midway point where …