Cell death is an important facet of animal development. In some developing tissues, death is
the ultimate fate of over 80% of generated cells. Although recent studies have delineated a …

Gamete development is a fundamental process that is highly conserved from early
eukaryotes to mammals. As germ cells develop, they must coordinate a dynamic series of …

Oogenesis is a complex developmental process that involves spatiotemporally regulated
coordination between the germline and supporting, somatic cell populations. This process …

Cooperative morphogenesis of cell lineages underlies the development of functional units
and organs. To study mechanisms driving the coordination of lineages, we investigated …

Src family kinases (SFKs) are evolutionarily conserved proteins acting downstream of
receptors and regulating cellular processes including proliferation, adhesion, and migration …

Cell death is a fundamental aspect of development, homeostasis, and disease; yet, our
understanding of non-apoptotic forms of cell death is limited. One such form is phagoptosis …

Our understanding of the molecular pathways that regulate oogenesis and define cellular
identity in the Arthropod female reproductive system and the extent of their conservation is …

The Drosophila ovary offers a suitable model system to study the mechanisms that
orchestrate diverse cellular processes. Oogenesis starts from asymmetric stem cell division …

Xenopus oocytes are encompassed by a layer of follicular cells that contribute to oocyte
growth and meiosis in relation to oocyte maturation. However, the effects of the interaction …

Cell proliferation and cell death are two opposing, yet complementary fundamental
processes in development. Cell proliferation provides new cells, while developmental …