Brain endocannabinoid (eCB) signalling influences the motivation for natural rewards (such
as palatable food, sexual activity and social interaction) and modulates the rewarding effects …

The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

As our understanding of the endocannabinoids improves, so does the awareness of their
complexity. During pathological states, the levels of these mediators in tissues change, and …

The high heterogeneity of psychiatric disorders leads to a lack of diagnostic precision.
Therefore, the search of biomarkers is a fundamental aspect in psychiatry to reach a more …

Background: The 21-item Three-Factor Eating Questionnaire (TFEQ-R21) is a scale that
measures three domains of eating behavior: cognitive restraint (CR), uncontrolled eating …

Marijuana and its major psychotropic component, Δ9-tetrahydrocannabinol, stimulate
appetite and increase body weight in wasting syndromes, suggesting that the CB1 …

The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …

Context: Cannabinoid CB1 receptor blockade decreases weight and hyperinsulinemia in
obese animals and humans in a way greatly independent from food intake. Objective: The …

Two receptors have been cloned to date for the psychotropic compound Δ 9-
tetrahydrocannabinol, and termed cannabinoid CB 1 and CB 2 receptors. Their endogenous …

2-Arachidonoylglycerol (2-AG) is a unique molecular species of monoacylglycerol isolated
in 1995 from rat brain and canine gut as an endogenous ligand for the cannabinoid …