The extracellular signal-regulated kinase (ERK) cascade is a central pathway that transmits
signals from many extracellular agents to regulate cellular processes such as proliferation …

The ERK signaling cascade is a central MAPK pathway that plays a role in the regulation of
various cellular processes such as proliferation, differentiation, development, learning …

Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers.
However, treatment with cisplatin is associated with drug resistance and several adverse …

ERK1/2 is an important subfamily of mitogen‐activated protein kinases that control a broad
range of cellular activities and physiological processes. ERK1/2 can be activated transiently …

Cellular signal transduction is a complex process involving protein-protein interactions
(PPIs) that transmit information. For example, signals from the plasma membrane may be …

Mitogen-activated protein kinase dual-specificity phosphatase-1 (also called MKP-1,
DUSP1, ERP, CL100, HVH1, PTPN10, and 3CH134) is a member of the threonine-tyrosine …

Dual-specificity phosphatases (DUSPs) are a subset of protein tyrosine phosphatases, many
of which dephosphorylate threonine and tyrosine residues on mitogen-activated protein …

Sequential activation of protein kinases within the mitogen-activated protein kinase (MAPK)
cascades is a common mechanism of signal transduction in many cellular processes. Four …

Muscle fibres have different properties with respect to force, contraction speed, endurance,
oxidative/glycolytic capacity etc. Although adult muscle fibres are normally post‐mitotic with …

It has generally been believed that the diffusion limit set by the nuclear pore for protein is
60kDa. We here studied the cellular localization of several artificial proteins and found that …