Hyaluronan in wound healing: rediscovering a major player

KL Aya, R Stern - Wound repair and regeneration, 2014 - Wiley Online Library
Wound healing involves a series of carefully modulated steps, from initial injury and blood
clot to the final reconstituted tissue or scar. A dynamic reciprocity exists throughout between …

Mesenchymal stem cell-derived extracellular vesicles as mediators of anti-inflammatory effects: endorsement of macrophage polarization

C Lo Sicco, D Reverberi, C Balbi, V Ulivi… - Stem cells …, 2017 - academic.oup.com
Abstract Mesenchymal Stem Cells (MSCs) are effective therapeutic agents enhancing the
repair of injured tissues mostly through their paracrine activity. Increasing evidences show …

[HTML][HTML] Phenotype, function, and differentiation potential of human monocyte subsets

LB Boyette, C Macedo, K Hadi, BD Elinoff, JT Walters… - PloS one, 2017 - journals.plos.org
Human monocytes have been grouped into classical (CD14++ CD16−), non-classical
(CD14dimCD16++), and intermediate (CD14++ CD16+) subsets. Documentation of normal …

Macrophages of diverse phenotypes drive vascularization of engineered tissues

PL Graney, S Ben-Shaul, S Landau, A Bajpai… - Science …, 2020 - science.org
Macrophages are key contributors to vascularization, but the mechanisms behind their
actions are not understood. Here, we show that diverse macrophage phenotypes have …

Assessing identity, phenotype, and fate of endothelial progenitor cells

KK Hirschi, DA Ingram, MC Yoder - … , thrombosis, and vascular …, 2008 - Am Heart Assoc
the Asahara at al10 article, human CD34 expressing cells (15.7% enriched for CD34
expression) in adult peripheral blood were interrogated as putative EPCs via in vitro and in …

Arteriogenesis versus angiogenesis: similarities and differences

M Heil, I Eitenmüller, T Schmitz‐Rixen… - Journal of cellular …, 2006 - Wiley Online Library
Cardiovascular diseases account for more than half of total mortality before the age of 75 in
industrialized countries. To develop therapies promoting the compensatory growth of blood …

Extracellular matrix, inflammation, and the angiogenic response

AG Arroyo, ML Iruela-Arispe - Cardiovascular research, 2010 - academic.oup.com
Inflammation and angiogenesis are frequently coupled in pathological situations such as
atherosclerosis, diabetes, and arthritis. The inflammatory response increases capillary …

Transdermal regulation of vascular network bioengineering using a photopolymerizable methacrylated gelatin hydrogel

RZ Lin, YC Chen, R Moreno-Luna, A Khademhosseini… - Biomaterials, 2013 - Elsevier
The search for hydrogel materials compatible with vascular morphogenesis is an active area
of investigation in tissue engineering. One candidate material is methacrylated gelatin …

[HTML][HTML] Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft

S Gazzaniga, AI Bravo, A Guglielmotti… - Journal of Investigative …, 2007 - Elsevier
Chemokines such as monocyte chemoattractant protein (MCP)-1 are key agonists that
attract macrophages to tumors. In melanoma, it has been previously shown that variable …

In vivo models of angiogenesis

K Norrby - Journal of cellular and molecular medicine, 2006 - Wiley Online Library
The process of building new blood vessels (angiogenesis) and controlling the propagation
of blood vessels (anti‐angiogenesis) are fundamental to human health, as they play key …