Human skin is the largest organ and serves as the first line of defense against environmental
factors. The human microbiota is defined as the total microbial community that coexists in the …

Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …

Psoriasis is a chronic immune-dysregulated inflammatory disease and hypovitaminosis D is
considered a risk factor. We conducted an online database search to review and meta …

Although conventional topical approaches for treating psoriasis have been offered as an
alternative, there are still unmet medical needs such as low skin-penetrating efficacy and off …

Background In addition to its barrier function, the skin plays a crucial role in maintaining the
stability of the body's internal environment and normal physiological functions. When the …

TRPV1 is a non-selective channel receptor widely expressed in skin tissues, including
keratinocytes, peripheral sensory nerve fibers and immune cells. It is activated by a variety of …

Ethnopharmacological relevance Centella asiatica (L.) Urban (CA) is a dry herb of the
Umbelliferae family, first mentioned in Shennong's Herbal Classic. It is known for its ability to …

An intact barrier function of the skin is important in maintaining skin health. The regulation of
the skin barrier depends on a multitude of molecular and immunological signaling pathways …

Abstract Zonula occludens‐1 (ZO‐1) is a scaffolding protein of tight junctions, which seal
adjacent epithelial cells, that is also expressed in adherens junctions. The distribution …

Psoriasis is a chronic inflammatory skin disease that features localized or widespread
erythema, papules, and scaling. It is common worldwide and may be distributed throughout …