11. Chronic Kidney Disease and Risk Management: Standards of Care in Diabetes—2023

NA ElSayed, G Aleppo, VR Aroda, RR Bannuru… - Diabetes …, 2023 - Am Diabetes Assoc
The American Diabetes Association (ADA)“Standards of Care in Diabetes” includes the
ADA's current clinical practice recommendations and is intended to provide the components …

11. Chronic Kidney Disease and Risk Management: Standards of Medical Care in Diabetes—2022

American Diabetes Association Professional … - Diabetes …, 2022 - Am Diabetes Assoc
The American Diabetes Association (ADA)“Standards of Medical Care in Diabetes” includes
the ADA's current clinical practice recommendations and is intended to provide the …

Chronic kidney disease

K Kalantar-Zadeh, TH Jafar, D Nitsch, BL Neuen… - The lancet, 2021 - thelancet.com
Chronic kidney disease is a progressive disease with no cure and high morbidity and
mortality that occurs commonly in the general adult population, especially in people with …

Effects of SGLT2 inhibitors on kidney and cardiovascular function

V Vallon, S Verma - Annual review of physiology, 2021 - annualreviews.org
SGLT2 inhibitors are antihyperglycemic drugs that protect kidneys and the heart of patients
with or without type 2 diabetes and preserved or reduced kidney function from failing. The …

The current role of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes mellitus management

B Xu, S Li, B Kang, J Zhou - Cardiovascular diabetology, 2022 - Springer
Type 2 diabetes mellitus (T2DM) is a chronic, complex metabolic disease characterized by
chronic hyperglycemia causing from insufficient insulin signaling because of insulin …

Mechanisms of Cardiorenal Effects of Sodium-Glucose Cotransporter 2 Inhibitors: JACC State-of-the-Art Review

TA Zelniker, E Braunwald - Journal of the American College of Cardiology, 2020 - jacc.org
Sodium-glucose cotransporter 2 inhibitors (SGLT2i), a new drug class approved for
treatment of diabetes, have been shown to possess a favorable metabolic profile and to …

Sodium–glucose cotransporter type 2 inhibitors for the treatment of type 2 diabetes mellitus

AJ Scheen - Nature reviews endocrinology, 2020 - nature.com
The management of type 2 diabetes mellitus (T2DM) is becoming increasingly complex.
Sodium–glucose cotransporter type 2 inhibitors (SGLT2is) are the newest antidiabetic …

The tubular hypothesis of nephron filtration and diabetic kidney disease

V Vallon, SC Thomson - Nature Reviews Nephrology, 2020 - nature.com
Kidney size and glomerular filtration rate (GFR) often increase with the onset of diabetes,
and elevated GFR is a risk factor for the development of diabetic kidney disease …

Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials

V Perkovic, D de Zeeuw, KW Mahaffey… - The lancet Diabetes & …, 2018 - thelancet.com
Summary Background In the Canagliflozin Cardiovascular Assessment Study (CANVAS)
Program, canagliflozin reduced the rates of major adverse cardiovascular events and the …

The impact of CKD on uremic toxins and gut microbiota

J Rysz, B Franczyk, J Ławiński, R Olszewski… - Toxins, 2021 - mdpi.com
Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …